1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl

Base Information

• Chemical Name: 1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl
• CAS No.: 216574-70-8
• Molecular Formula: C11H18 N2 O2
• Molecular Weight: 210.276
• Mol file: 216574-70-8.mol

Synonyms:1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl

Chemical Property of 1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl

Chemical Property:

• Boiling Point: 320.2±42.0 °C(Predicted)
• PKA: 3.51±0.14(Predicted)
• PSA: 57.25000
• Density: 1.08±0.1 g/cm3(Predicted)
• LogP: 2.27260

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl

There total 1 articles about 1H-Pyrrole-2-carboxylicacid,3-amino-5-(1,1-dimethylethyl)-1-methyl-,methyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ methyl 3-amino-5-tert-butyl-1-methylpyrrole-2carboxylate (216574-70-8)

Guidance literature:

Reference yield: 69.0%

phosgene (75-44-5) + p-toluidine (106-49-0,12221-03-3) + methyl 3-amino-5-tert-butyl-1-methylpyrrole-2carboxylate (216574-70-8) → 5-tert-butyl-1-methyl-3-(3-p-tolyl-ureido)-1H-pyrrole-2-carboxylic acid methyl ester

Guidance literature:

phosgene; methyl 3-amino-5-tert-butyl-1-methylpyrrole-2carboxylate; With pyridine; In toluene; for 0.5h;

p-toluidine;

Reference yield: 69.0%

phosgene (75-44-5) + p-toluidine (106-49-0,12221-03-3) + methyl 3-amino-5-tert-butyl-1-methylpyrrole-2carboxylate (216574-70-8) → N-(N-methyl-2-carbomethoxy-5-tert-butyl-3-pyrrolyl)-N'-(4-methyl-thien-2-yl)urea + N-(2-Carbomethoxy-5-tert-butyl-3-pyrrolyl)-N'-(phenyl)urea

Guidance literature:

With pyridine; In toluene;