tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate

Base Information

• Chemical Name: tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate
• CAS No.: 1021490-99-2
• Molecular Formula: C₃₇H₃₈O₇S
• Molecular Weight: 626.771
• Mol file: 1021490-99-2.mol

Synonyms:tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate

Chemical Property of tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate

There total 1 articles about tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside (1021490-97-0) + tert-butyl alcohol (75-65-0) → tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate (1021490-99-2)

Guidance literature:

With dipyridinium dichromate; acetic anhydride; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.carres.2007.12.015

Reference yield: 88.0%

tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate (1021490-99-2) + [(2S,3R,4R,5S,6R)-4-Benzyloxy-5-hydroxy-2-methoxy-6-(4-methoxy-phenoxymethyl)-tetrahydro-pyran-3-yl]-carbamic acid benzyl ester (117129-62-1) → methyl [tert-butyl (2-O-benzoyl-3,4-di-O-benzyl-α-L-idopyranosyl)uronate]-(1->4)-3-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-6-O-(4-methoxy)phenyl-α-D-glucopyranoside (1021491-05-3)

Guidance literature:

With dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.carres.2007.12.015

Reference yield: 86.0%

tert-butyl (phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside)uronate (1021490-99-2) + methyl N-benzyloxycarbonyl-2-deoxy-3,6-di-O-benzylglucopyranoside (110236-56-1) → methyl [tert-butyl (2-O-benzoyl-3,4-di-O-benzyl-α-L-idopyranosyl)uronate]-(1->4)-3,6-di-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside (1021491-04-2)

Guidance literature:

With dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.carres.2007.12.015

upstream raw materials:

phenyl 2-O-benzoyl-3,4-di-O-benzyl-1-thio-α-L-idopyranoside

tert-butyl alcohol

Downstream raw materials:

methyl [tert-butyl (2-O-benzoyl-3,4-di-O-benzyl-α-L-idopyranosyl)uronate]-(1->4)-3,6-di-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-α-D-glucopyranoside

methyl [tert-butyl (2-O-benzoyl-3,4-di-O-benzyl-α-L-idopyranosyl)uronate]-(1->4)-3-O-benzyl-2-benzyloxycarbonylamino-2-deoxy-6-O-(4-methoxy)phenyl-α-D-glucopyranoside

methyl (tert-butyl 2-O-benzoyl-3,4-di-O-benzyl-α-L-idopyranosyluronate)-(1->4)-[2-azido-3-O-benzyl-2-deoxy-6-O-(4-methoxyphenyl)-α-D-glucopyranosyl]-(1->4)-(tert-butyl 2-O-benzoyl-3-O-benzyl-α-L-idopyranosideuronate)