2-Methoxy-4-methylbenzenesulfonyl chloride

Base Information

Chemical Name:2-Methoxy-4-methylbenzenesulfonyl chloride
CAS No.:216394-11-5
Molecular Formula:C8H9ClO3S
Molecular Weight:220.677
Hs Code.:2909309090
European Community (EC) Number:679-155-7
DSSTox Substance ID:DTXSID70463022
Wikidata:Q82287729
Mol file:216394-11-5.mol

Synonyms:216394-11-5;2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE;2-Methoxy-4-methylbenzene-1-sulfonyl chloride;2-methoxy-4-methyl-benzenesulfonyl Chloride;Benzenesulfonyl chloride, 2-methoxy-4-methyl-;2-methoxy-4-methylbenzenesulfonylchloride;2-Methoxy-4-methylbenzenesulphonyl chloride;SCHEMBL533956;DTXSID70463022;BEDNMYGUVYQPTP-UHFFFAOYSA-N;AMY42045;BCP21984;MFCD01318157;AKOS005139312;2-methoxy4-methyl-benzenesulfonylchloride;2-methoxy-4-methylbenzensulfonyl chloride;2-Methoxy-4-methylphenylsulfonyl chloride;2-methoxy-4-methyl-benzenesulfonylchloride;2-Methoxy-4-methylbenzene-1-sulfonylchloride;FT-0612794;EN300-111721;A815565;2-methoxy-4-methylbenzenesulfonyl chloride, AldrichCPR

Suppliers and Price of 2-Methoxy-4-methylbenzenesulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Methoxy-4-methylbenzene-1-sulfonylchloride 95%
1g
$ 1280.00

American Custom Chemicals Corporation
2-METHOXY-4-METHYLBENZENESULFONYL CHLORIDE 95.00%
5MG
$ 505.73

AHH
2-Methoxy-4-methylbenzenesulfonylchloride 98%
25g
$ 538.00

Total 23 raw suppliers

Chemical Property of 2-Methoxy-4-methylbenzenesulfonyl chloride

Chemical Property:

Vapor Pressure:0.000614mmHg at 25°C
Melting Point:87-89 °C
Refractive Index:1.529
Boiling Point:319.9 °C at 760 mmHg
Flash Point:147.3 °C
PSA：51.75000
Density:1.326 g/cm³
LogP:3.01190
Storage Temp.:2-8°C
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:219.9960930
Heavy Atom Count:13
Complexity:257

Purity/Quality:

98% ^*data from raw suppliers

2-Methoxy-4-methylbenzene-1-sulfonylchloride 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R34:Causes burns.;
Hazard Codes:R34:Causes burns.;
Statements: R34:Causes burns.;
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)S(=O)(=O)Cl)OC

Technology Process of 2-Methoxy-4-methylbenzenesulfonyl chloride

There total 6 articles about 2-Methoxy-4-methylbenzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59554-29-9
3-methoxy-toluene-4-sulfonic acid

: 216394-11-5
2-methoxy-4-methylbenzenesulfonyl chloride

Guidance literature:: With thionyl chloride; In hexane; dichloromethane; water;

Reference yield:

: 27060-75-9
4-bromo-3-methylanisole

: 216394-11-5
2-methoxy-4-methylbenzenesulfonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 16 h / 20 - 40 °C

2: palladium 10% on activated carbon; hydrogen / methanol / 7 h / 60 °C / 3620.13 Torr

3: thionyl chloride / 2 h / Reflux

With thionyl chloride; sulfuric acid; palladium 10% on activated carbon; hydrogen; In methanol;

Reference yield:

: C₈H₉BrO₄S

: 216394-11-5
2-methoxy-4-methylbenzenesulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 7 h / 60 °C / 3620.13 Torr

2: thionyl chloride / 2 h / Reflux

With thionyl chloride; palladium 10% on activated carbon; hydrogen; In methanol;