27060-75-9

Basic information

• Product Name: 2-Bromo-5-methoxytoluene
• Synonyms: 2-Bromo-5-methoxytoluene, 1-Bromo-4-methoxy-2-methylbenzene, 4-Bromo-3-methylphenyl methyl ether;2-BroMo-5-Methoxytoluene (BMA);4-BroMo-3-Methylanisole, 97%, 97%;2-Bromo-4-methoxy-1-methylbenzene;1-BROMO-4-METHOXY-2-METHYLBENZENE;2-BROMO-5-METHOXYTOLUENE;3-Methyl-4-bromoanisole;4-BROMO-3-METHYLANISOLE
• CAS NO: 27060-75-9
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.06
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene;Anisoles, Alkyloxy Compounds & Phenylacetates;Bromine Compounds
• Mol File: 27060-75-9.mol
• Article Data: 47

Chemical Properties

• Melting Point: 16.5 °C
• Boiling Point: 111-112 °C15 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Clear colorless to slightly yellow/Liquid
• Density: 1.424 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0773mmHg at 25°C
• Refractive Index: n20/D 1.561(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: water: soluble (Partially miscible)(lit.)
• BRN: 1933865
• CAS DataBase Reference: 2-Bromo-5-methoxytoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-methoxytoluene(27060-75-9)
• EPA Substance Registry System: 2-Bromo-5-methoxytoluene(27060-75-9)

Safety Data

• Hazard Codes: Xi
• Safety Statements: 24/25
• WGK Germany: 3
• TSCA: Yes
• Hazardous Substances Data: 27060-75-9(Hazardous Substances Data)

Usage

Chemical Properties

colorless to light yellow liquid

InChI:InChI=1/C8H9BrO/c1-6-5-7(10-2)3-4-8(6)9/h3-5H,1-2H3

Upstream product

• 14472-14-1 4-bromo-3-methylphenol 
• 77-78-1 dimethyl sulfate 
• 102-50-1 2-methyl-4-methoxyaniline 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 74-88-4 methyl iodide 
• 52289-55-1 (4-methoxy-2-methylphenyl)methanol 
• 6245-57-4 4-methoxy-2-methylbenzoic acid 
• 128-08-5 N-Bromosuccinimide 
• 76006-33-2 3-bromo-2-methylbenzoic acid 
• 121-43-7 Trimethyl borate 
• 5367-32-8 5-methoxy-2-nitrotoluene 
• 108-39-4 3-methyl-phenol 
• 59554-30-2 5-methoxy-toluene-2-sulfonic acid 
• 7732-18-5 water 

Downstream Products

• 104178-07-6 5-Methoxy-2-dimethylaminomethyl-toluol 
• 30888-95-0 2-(4-methoxy-2-methylphenyl)ethanol 
• 63121-53-9 p-Methoxy-o-tolyldi-tert.-butylcarbinol 
• 35932-65-1 1-(5-Bromo-2-methoxy-4-methyl-phenyl)-cyclohexanol 
• 174810-40-3 (E)-3-(4-methoxy-2-methylphenyl)acrylic acid tert-butyl ester 
• 521958-77-0 2-(4-methoxy-2-methylphenyl)-pyridine 
• 21883-13-6 4-methoxy-2-methylbenzonitrile 
• 471261-26-4 (S)-5-(tert-Butyl-diphenyl-silanyloxy)-1-(4-methoxy-2-methyl-phenyl)-pentan-2-ol 
• 208399-66-0 4-methoxy-2-methylphenyl boronic acid 
• 100-84-5 1-methoxy-3-methyl-benzene 
• 934996-88-0 allyl 4-methoxy-2-methylphenyl selenide 
• 392657-97-5 2-chloro-6-(4-methoxy-2-methyl-phenyl)-4-phenyl-pyridine 

Relevant articles and documents

Visible light-induced mono-bromination of arenes with BrCCl3

A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using commercially available BrCCl3as a “Br” source has been developed. The reaction was performed in air under mild conditions with photocatalyst Ru(bpy)3Cl2·6H2O, avoiding the usage of strong acids and strong oxidants. Mono-brominated products were obtained with medium to excellent yields (up to 94%). This strategy has shown good compatibility and highpara-selectivity, which will facilitate the complicated synthesis.

Environmentally benign indole-catalyzed position-selective halogenation of thioarenes and other aromatics

Halogenated aromatic compounds are the cores of many pharmaceutical, agricultural and chemical products but they are commonly prepared using electrophilic halogenation reactions in non-green chlorinated solvents under harsh conditions. A separate problem happens in the aromatic halogenation of thioarenes because they readily undergo oxidative side-reactions. Herein we report an environmentally benign electrophilic bromination of aromatics using an indole-catalytic protocol, which is suitable for a wide range of substrates including thioarenes.

Micro reaction system and method for synthesizing 4-bromo-3-methylanisole through two-phase method

The invention discloses a micro reaction system and method for synthesizing 4-bromo-3-methylanisole through a two-phase method, and belongs to the technical field of chemical engineering. The micro reaction system comprises a micro mixer, a micro packed b