1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile

Base Information

Chemical Name:1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile
CAS No.:215794-24-4
Molecular Formula:C10H10N2
Molecular Weight:194.66
Hs Code.:2933499090
European Community (EC) Number:676-248-4
DSSTox Substance ID:DTXSID30585678
Wikidata:Q72505865
Mol file:215794-24-4.mol

Synonyms:1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile;215794-24-4;1,2,3,4-TETRAHYDRO-ISOQUINOLINE-5-CARBONITRILE;1,2,3,4-TETRAHYDRO-5-ISOQUINOLINECARBONITRILE;SCHEMBL1010480;DTXSID30585678;BTLCQUCMNTUJNV-UHFFFAOYSA-N;MFCD07369985;AKOS006343493;AB32479;AS-38464;A4638;CS-0058560;A13057;EN300-219388;Q-102337;1,2,3,4-tetrahydro-isoquinoline-5-carbonitrile, AldrichCPR

Suppliers and Price of 1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,2,3,4-tetrahydroisoquinoline-5-carbonitrile
100mg
$ 265.00

SynQuest Laboratories
1,2,3,4-Tetrahydro-isoquinoline-5-carbonitrile 95%
1 g
$ 1592.00

SynQuest Laboratories
1,2,3,4-Tetrahydro-isoquinoline-5-carbonitrile 95%
250 mg
$ 816.00

SynQuest Laboratories
1,2,3,4-Tetrahydro-isoquinoline-5-carbonitrile 95%
100 mg
$ 600.00

Crysdot
1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile 97%
1g
$ 470.00

Chemenu
1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile 97%
10g
$ 1595.00

Chemenu
1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile 97%
5g
$ 1062.00

Chemenu
1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile 97%
1g
$ 439.00

Apolloscientific
1,2,3,4-Tetrahydro-isoquinoline-5-carbonitrile 95%
100mg
$ 544.00

Apolloscientific
1,2,3,4-Tetrahydro-isoquinoline-5-carbonitrile 95%
250mg
$ 740.00

Total 35 raw suppliers

Chemical Property of 1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile

Chemical Property:

Vapor Pressure:0.000388mmHg at 25°C
Refractive Index:1.595
Boiling Point:317.3 °C at 760 mmHg
PKA:8.55±0.20(Predicted)
Flash Point:145.7 °C
PSA：35.82000
Density:1.14 g/cm³
LogP:1.53278
Storage Temp.:2-8°C
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:158.084398327
Heavy Atom Count:12
Complexity:203

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,4-tetrahydroisoquinoline-5-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CNCC2=C1C(=CC=C2)C#N

Technology Process of 1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile

There total 1 articles about 1,2,3,4-Tetrahydroisoquinoline-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 557-21-1
zinc(II) cyanide

: 81237-69-6
5-bromo-1,2,3,4-tetrahydro-isoquinoline

: 215794-24-4
1,2,3,4-tetrahydroisoquinoline-5-carbonitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 100 ℃; for 15h; Inert atmosphere;

Reference yield: 14.0%

: 14305-08-9
4,5-dibromo-2-phenylpyridazin-3(2H)-one

: 215794-24-4
1,2,3,4-tetrahydroisoquinoline-5-carbonitrile

: 1549705-88-5
2-(5-bromo-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)-1,2,3,4-tetrahydroisoquinoline-5-carbonitrile

Guidance literature:: In ethanol; for 16h; Reflux;
DOI:10.1016/j.bmc.2013.12.041

Reference yield:

: 215794-24-4
1,2,3,4-tetrahydroisoquinoline-5-carbonitrile

: C₃₂H₂₈ClN₇O₄

Guidance literature:: Multi-step reaction with 2 steps

1: manganese(IV) oxide / dichloromethane

2: ethanol / 24 h / Reflux

With manganese(IV) oxide; In ethanol; dichloromethane; 2: |Ugi Condensation;