14305-08-9

Basic information

• Product Name: 4,5-DIBROMO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE
• Synonyms: BUTTPARK 154\16-22;4,5-DIBROMO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE;4,5-DIBROMO-2-PHENYL-3(2H)-PYRIDAZINONE;4,5-DIBROMO-2-PHENYLPYRIDAZIN-3(2H)-ONE;4,5-dibromo-2-phenyl-3(2h)-pyridazinon;4,5-DIBROMO-2-PHENYLPYRIDAZINE-3(2H)-ONE;4,5-dibromo-2-phenyl-3-pyridazinone;4,5-Dibromo-2-phenyl-2H-pyridazin-3-one
• CAS NO: 14305-08-9
• Molecular Formula: C₁₀H₆Br₂N₂O
• Molecular Weight: 329.98
• EINECS: 200-001-2
• Product Categories: Halides;Pyrazines, Pyrimidines & Pyridazines;Pyrazines, Pyrimidines & Pyridazines
• Mol File: 14305-08-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 143℃
• Boiling Point: 340.1 °C at 760 mmHg
• Flash Point: 159.5 °C
• Appearance: /
• Density: 1.89 g/cm³
• Vapor Pressure: 8.82E-05mmHg at 25°C
• Refractive Index: 1.687
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4,5-DIBROMO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5-DIBROMO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE(14305-08-9)
• EPA Substance Registry System: 4,5-DIBROMO-2-PHENYL-2,3-DIHYDROPYRIDAZIN-3-ONE(14305-08-9)

Safety Data

• Hazard Codes: Xi
• Statements: R36/37/38:Irritating to eyes, respiratory system and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g
• Hazardous Substances Data: 14305-08-9(Hazardous Substances Data)

Usage

Uses

4,5-Dibromo-2-phenylpyridazin-3(2H)-one (cas# 14305-08-9) is a useful research chemical.

InChI:InChI=1/C10H6Br2N2O/c11-8-6-13-14(10(15)9(8)12)7-4-2-1-3-5-7/h1-6H

Upstream product

• 21577-50-4 mucobromic acid 
• 100-63-0 phenylhydrazine 
• 488-11-9 mucobromic acid 
• 766-38-1 mucobromic acid 
• 62-53-3 aniline 

Downstream Products

• 21456-76-8 4-bromo-2-phenyl-5-piperidino-2H-pyridazin-3-one 
• 21456-77-9 4-bromo-5-morpholino-2-phenylpyridazin-3(2H)-one 
• 10002-74-1 4-bromo-5-ethoxy-2-phenyl-2H-pyridazin-3-one 
• 21456-72-4 4-bromo-5-methylamino-2-phenyl-2H-pyridazin-3-one 
• 38321-78-7 4-bromo-5-hydroxy-2-phenyl-2H-pyridazin-3-one 
• 67397-23-3 5-ethoxy-2-phenyl-2H-pyridazin-3-one 
• 1549708-99-7 2-phenyl-4-isopropyl-5-bromopyridazin-3(2H)-one 
• 1549705-95-4 4-bromo-2-phenyl-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)pyridazin-3(2H)-one 
• 1549706-46-8 5-(4-acetyl-5-methyl-1H-1,2,3-triazol-1-yl)-4-isopropyl-2-phenylpyridazin-3(2H)-one 
• 1549709-41-2 5-azido-4-isopropyl-2-phenylpyridazin-3(2H)-one 
• 28081-44-9 5-(4-acetyl-5-methyl-1H-1,2,3-triazol-1-yl)-4-bromo-2-phenylpyridazin-3(2H)-one 
• 1549705-88-5 2-(5-bromo-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)-1,2,3,4-tetrahydroisoquinoline-5-carbonitrile 
• 1549706-05-9 2-((5-bromo-6-oxo-1-phenyl-1,6-dihydropyridazin-4-yl)amino)acetamide 
• 1549706-16-2 4-bromo-2-phenyl-5-(((tetrahydrofuran-2-yl)methyl)amino)pyridazin-3(2H)-one 

Relevant articles and documents

Discovery of 5-substituted-N-arylpyridazinones as inhibitors of p38 MAP kinase

The synthesis, structure-activity relationship and modeling of a series of 5-substituted-N-aryl pyridazinone based p38α inhibitors are described. In comparing the series to the similar N-aryl pyridinone series, it was found that the pyridazinones maintain

Substituted pyridazinones

Disclosed are substituted pyridazinones that are useful for treating diseases and conditions caused or exacerbated by unregulated p38 MAP Kinase and/or TNF activity. Pharmaceutical composition containing the pyridazinone compounds, methods of preparing th