ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Base Information

Chemical Name:ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate
CAS No.:1416153-62-2
Molecular Formula:C₃₁H₃₃NO₇S₂
Molecular Weight:595.738
Hs Code.:

Synonyms:ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Suppliers and Price of ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

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Technology Process of ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

There total 4 articles about ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 2528-00-9
5-Chloromethyl-furan-2-carboxylic acid ethyl ester

: 2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide

: 1416153-62-2
ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Guidance literature:: With potassium carbonate; In acetonitrile; for 2h; Microwave irradiation; Heating;
DOI:10.1016/j.bioorg.2021.105540

Reference yield:

: 1055339-40-6
N-(4-bromobenzyl)-2,4,6-trimethylbenzenesulfonamide

: 1416153-62-2
ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: palladium diacetate; tris-(o-tolyl)phosphine; potassium carbonate / 1,4-dioxane / 120 °C / Inert atmosphere

2: potassium carbonate / acetone / 2 h / 65 °C / Microwave irradiation

With palladium diacetate; potassium carbonate; tris-(o-tolyl)phosphine; In 1,4-dioxane; acetone;

Reference yield:

: 773-64-8
2-mesitylenesulphonyl chloride

: 1416153-62-2
ethyl 5-((2,4,6-trimethyl-N-((3'-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)methyl)phenylsulfonamido)methyl)furan-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 1 h / 20 °C

2: palladium diacetate; tris-(o-tolyl)phosphine; potassium carbonate / 1,4-dioxane / 120 °C / Inert atmosphere

3: potassium carbonate / acetone / 2 h / 65 °C / Microwave irradiation

With palladium diacetate; potassium carbonate; triethylamine; tris-(o-tolyl)phosphine; In 1,4-dioxane; dichloromethane; acetone;