Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)

Base Information

Chemical Name:Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)
CAS No.:214679-14-8
Molecular Formula:C₁₀H₂₁NO₃
Molecular Weight:203.282
Hs Code.:
Mol file:214679-14-8.mol

Synonyms:Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)

Suppliers and Price of Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

Boiling Point:309.1±25.0 °C(Predicted)
PKA:12.39±0.46(Predicted)
PSA：58.56000
Density:0.997±0.06 g/cm3(Predicted)
LogP:2.06300

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI)

There total 8 articles about Carbamic acid, [(2R)-2-hydroxypentyl]-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 214679-10-4
(1S,2R,1'R)-(-)-N-<2-(1'-tert-butoxycarbonylaminomethylbutoxy)-1-methyl-2-phenylethyl>formamide

: 15547-39-4,15302-18-8
N-<(S)-1-methyl-2-phenylethyl>formamide

: 214679-14-8
(2R)-(-)-1-tert-butoxycarbonylaminopentan-2-ol

Guidance literature:: With sodium; In tetrahydrofuran; ammonia; at -78 ℃; for 0.25h; Yields of byproduct given;
DOI:10.1002/(sici)1099-0690(199809)1998:9<1771::aid-ejoc1771>3.0.co;2-p

Reference yield: 61.0%

: 1003-14-1
2-pentyloxirane

: 4248-19-5
tert-butyl carbazate

: 214679-14-8
(2R)-(-)-1-tert-butoxycarbonylaminopentan-2-ol

Guidance literature:: tert-butyl carbazate; With [(S,S)-N,N’-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminato(2-)]cobalt(II); 4-nitro-benzoic acid; In tert-butyl methyl ether; for 0.0833333h;

2-pentyloxirane; In tert-butyl methyl ether; at 20 ℃; for 24h; enantioselective reaction;
DOI:10.1021/acs.jmedchem.0c02207

Reference yield: 56.0%

: 1003-14-1
2-pentyloxirane

: 4248-19-5
tert-butyl carbazate

: 214679-14-8
(S)-tert-butyl (2-hydroxypentyl)carbamate

Guidance literature:: tert-butyl carbazate; With (1R,2R)-(-)-N,N'-bis(3,5-di-tert-butylsalicydene)-1,2-cyclohexanediaminocobalt(II); 4-nitro-benzoic acid; In tert-butyl methyl ether; for 0.0833333h;

2-pentyloxirane; In tert-butyl methyl ether; at 20 ℃; for 24h; enantioselective reaction;
DOI:10.1021/acs.jmedchem.0c02207