5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine

Base Information

• Chemical Name: 5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine
• CAS No.: 1148021-54-8
• Molecular Formula: C₂₁H₁₇BrN₄O₃
• Molecular Weight: 453.295
• Mol file: 1148021-54-8.mol

Synonyms:5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine

Chemical Property of 5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine

There total 1 articles about 5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline (1148021-50-4) → 5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine (1148021-54-8)

Guidance literature:

With formic acid; palladium 10% on activated carbon; triethylamine; In acetonitrile; at -15 ℃; chemoselective reaction; Reflux;

DOI:10.1021/jm1002952

Reference yield: 48.0%

5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine (1148021-54-8) → 5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine hydrochloride

Guidance literature:

With hydrogenchloride; In diethyl ether; acetone;

DOI:10.1021/jm1002952

Reference yield: 23.0%

5-(4''-bromo-2'',6''-dimethylphenoxy)-N1-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine (1148021-54-8) + acrylonitrile (107-13-1,25014-41-9) → N1-(4'-cyanophenyl)-5-(4'-propenylcyano-2',6'-dimethylphenoxy)-4-nitrobenzen e-1,2-diamine (1148021-70-8)

Guidance literature:

5-(4''-bromo-2'',6''-dimethylphenoxy)-N₁-(4'-cyanophenyl)-4-nitrobenzene-1,2-diamine; acrylonitrile; With triethylamine; palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; for 25h; Reflux; Inert atmosphere;

In water; N,N-dimethyl-formamide; Acidic aqueous solution;

upstream raw materials:

5-(4''-bromo-2'',6''-dimethylphenoxy)-N-(4'-cyanophenyl)-2,4-dinitroaniline

Downstream raw materials:

N₁-(4'-cyanophenyl)-5-(4'-propenylcyano-2',6'-dimethylphenoxy)-4-nitrobenzen e-1,2-diamine