methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

Base Information

Chemical Name:methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate
CAS No.:226718-00-9
Molecular Formula:C₂₂H₁₉F₂NO₄
Molecular Weight:399.394
Hs Code.:

Synonyms:methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

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Chemical Property of methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

Chemical Property:

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Technology Process of methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

There total 3 articles about methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5470-70-2
Methyl 6-methylnicotinate

: 226718-00-9
methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.75 h / in ice bath

2: 1.) Zn / 1.) THF, room t., 4 h, 2.) THF, in ice bath, 50 min

With zinc; In tetrahydrofuran;

Reference yield:

: 1885-14-9
phenyl chloroformate

: 226718-00-9
methyl 6-methyl-1-phenoxycarbonyl-4-(3,5-difluorobenzyl)-1,4-dihydronicotinate

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 0.75 h / in ice bath

2: 1.) Zn / 1.) THF, room t., 4 h, 2.) THF, in ice bath, 50 min

With zinc; In tetrahydrofuran;