Technology Process of C19H25NOS2Si
There total 3 articles about C19H25NOS2Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
6-(trimethylsilyl)hex-5-ynoic acid:;
With
dicyclohexyl-carbodiimide;
In
dichloromethane;
at -15 ℃;
for 0.5h;
Inert atmosphere;
(S)-4-benzylthiazolidin-2-thione;
With
dmap;
In
dichloromethane;
at 25 ℃;
Inert atmosphere;
DOI:10.1002/anie.201008000
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; n-butyllithium / tetrahydrofuran; hexane / -78 °C / Inert atmosphere
1.2: 2 h / 25 °C / Inert atmosphere
2.1: pyridinium dichromate / N,N-dimethyl-formamide / 12.4 h / 0 - 25 °C / Inert atmosphere
3.1: dicyclohexyl-carbodiimide / dichloromethane / 0.5 h / -15 °C / Inert atmosphere
3.2: 25 °C / Inert atmosphere
With
dmap; n-butyllithium; pyridinium dichromate; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/anie.201008000
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridinium dichromate / N,N-dimethyl-formamide / 12.4 h / 0 - 25 °C / Inert atmosphere
2.1: dicyclohexyl-carbodiimide / dichloromethane / 0.5 h / -15 °C / Inert atmosphere
2.2: 25 °C / Inert atmosphere
With
pyridinium dichromate; dicyclohexyl-carbodiimide;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/anie.201008000
