101224-43-5

Basic information

• Product Name: 5-Hexynoic acid, 6-(trimethylsilyl)-
• Synonyms: 5-Hexynoic acid,6-(trimethylsilyl);6-(trimethylsilyl)-5-hexynoic acid;6-(trimethylsilyl)hex-5-ynoic acid
• CAS NO: 101224-43-5
• Molecular Formula: C9H16O2Si
• Molecular Weight: 184.31
• Mol File: 101224-43-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Hexynoic acid, 6-(trimethylsilyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Hexynoic acid, 6-(trimethylsilyl)-(101224-43-5)
• EPA Substance Registry System: 5-Hexynoic acid, 6-(trimethylsilyl)-(101224-43-5)

Safety Data

• Hazardous Substances Data: 101224-43-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 60556-87-8 2-carbonyl-3-butenenitrile 
• 14657-22-8 allenyltrimethylsilane 

Downstream Products

• 1291101-88-6 C₁₉H₂₅NOS₂Si 
• 70667-26-4 (17S)-17,20-dimethyl-6-oxo-PGE₁ methyl ester 
• 382139-15-3 (5S,6S,8S,9S,10S,11S,12S,13S,15S)-15-(tert-Butyl-diphenyl-silanyloxymethyl)-10-(4-methoxy-benzyloxy)-5,9,11,13-tetramethyl-12-triethylsilanyloxy-1-trimethylsilanyl-heptadec-1-yne-6,8-diol 
• 382139-14-2 (4S,6S)-4-[(1S,2S,3S,4S,5S,7S)-7-(tert-Butyl-diphenyl-silanyloxymethyl)-2-(4-methoxy-benzyloxy)-1,3,5-trimethyl-4-triethylsilanyloxy-nonyl]-2,2-dimethyl-6-((S)-1-methyl-5-trimethylsilanyl-pent-4-ynyl)-[1,3]dioxane 
• 382138-93-4 (5S,8S,9S,10S,11S,12S,13S,15S)-15-(tert-Butyl-diphenyl-silanyloxymethyl)-8-hydroxy-10-(4-methoxy-benzyloxy)-5,9,11,13-tetramethyl-12-triethylsilanyloxy-1-trimethylsilanyl-heptadec-1-yn-6-one 
• 382139-17-5 2,2-Dimethyl-propionic acid (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonyl ester 
• 382138-97-8 (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonanoic acid methyl ester 
• 382139-18-6 (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonanoic acid amide 
• 382138-96-7 (2S,4S,5S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-triethylsilanyloxy-nonan-1-ol 
• 382139-16-4 2,2-Dimethyl-propionic acid (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-5-hydroxy-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonyl ester 
• 382138-98-9 (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-5-hydroxy-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonanoic acid amide 
• 382139-19-7 (2S,4S,6S,7S,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-5-oxo-nonanoic acid amide 
• 382138-95-6 (2S,4S,5S,6R,7R,8S)-8-[(4S,6S)-2,2-Dimethyl-6-((S)-1-methyl-pent-4-ynyl)-[1,3]dioxan-4-yl]-2-ethyl-7-(4-methoxy-benzyloxy)-4,6-dimethyl-nonane-1,5-diol 

Relevant articles and documents

α,β-Unsaturated Acyl Cyanides. 6. Self-Condensation and Conjugate Addition of Allyl, Allenyl-, Propargyl-, and Alkynyltrimethylsilanes

The base-induced reaction of α,β-unsaturated acyl cyanides leads to lactones resulting from a self condensation reaction.Neutral nucleophiles such as trimethylsilyl derivatives react with α,β-unsaturated acyl cyanides in the presence of titanium tetrachloride. δ-Ethylenic acyl cyanides, δ-acetylenic acyl cyanides, γ-allenic acyl cyanides, and γ-acetylenic acyl cyanides (or the corresponding acids or methyl esters) are obtained from α,β-unsaturated acyl cyanides by condensation respectively with allyl-, allenyl-, propargyl- and alkynyltrimethylsilanes.