(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

Base Information

Chemical Name:(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester
CAS No.:817625-25-5
Molecular Formula:C₁₉H₂₈N₂O₇
Molecular Weight:396.441
Hs Code.:

Synonyms:(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

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Chemical Property of (S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

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Technology Process of (S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

There total 2 articles about (S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 2788-84-3
(S)-serine methyl ester

: 23680-31-1
BOC-O-benzyl-L-serine

: 817625-25-5
(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In acetonitrile; at 20 ℃;

Reference yield: 99.0%

: 23680-31-1
BOC-O-benzyl-L-serine

: 5680-80-8
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

: 817625-25-5
(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; dicyclohexyl-carbodiimide; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

Reference yield: 99.0%

: 817625-25-5
(S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester

: 1095973-66-2
2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-(phenylmethoxy)ethyl]-2-(4S)-oxazoline methyl ester

Guidance literature:: (S)-2-((S)-3-benzyloxy-2-tert-butoxycarbonylaminopropionylamino)-3-hydroxypropionic acid methyl ester; With diethylamino-sulfur trifluoride; In dichloromethane; at -78 ℃; for 2.5h;

With potassium carbonate; In dichloromethane; at 20 ℃;

With sodium hydrogencarbonate; In dichloromethane; water;