1-Bromo-5-phenylnaphthalene

Base Information

• Chemical Name: 1-Bromo-5-phenylnaphthalene
• CAS No.: 911836-38-9
• Molecular Formula: C₁₆H₁₁Br
• Molecular Weight: 283.167
• DSSTox Substance ID: DTXSID60704794
• Wikidata: Q82637347
• Mol file: 911836-38-9.mol

Synonyms:1-Bromo-5-phenylnaphthalene;911836-38-9;SCHEMBL20033065;DTXSID60704794;FT-0707258

Chemical Property of 1-Bromo-5-phenylnaphthalene

Chemical Property:

• Boiling Point: 385.8±11.0 °C(Predicted)
• Density: 1.381±0.06 g/cm3(Predicted)
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 282.00441
• Heavy Atom Count: 17
• Complexity: 244

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=CC3=C2C=CC=C3Br

Technology Process of 1-Bromo-5-phenylnaphthalene

There total 7 articles about 1-Bromo-5-phenylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,5-dibromonaphthalene (7351-74-8) + phenylboronic acid (98-80-6) → 1-bromo-5-phenylnaphthalene (911836-38-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; at 70 ℃; for 5h; Inert atmosphere;

Reference yield:

5-bromo-1-tetralone (68449-30-9) → 1-bromo-5-phenylnaphthalene (911836-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / cooling

2: 50 mg / TFA; triphenylmethanol / 48 h

With triphenylmethyl alcohol; trifluoroacetic acid; In tetrahydrofuran; 1: Grignard reaction;

DOI:10.1021/ol061701p

Reference yield:

phenylmagnesium bromide → 1-bromo-5-phenylnaphthalene (911836-38-9)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran / cooling

2: 50 mg / TFA; triphenylmethanol / 48 h

With triphenylmethyl alcohol; trifluoroacetic acid; In tetrahydrofuran; 1: Grignard reaction;

DOI:10.1021/ol061701p

upstream raw materials:

5-bromo-1-phenyl-1,2,3,4-tetrahydro-naphthalen-1-ol

5-bromo-1-tetralone

1-bromo-5-nitronaphthalene

5-amino-1-bromonaphthalene

Downstream raw materials:

1'-deoxy-1'-β-(5-phenylnaphth-1-yl)-3',5'-bis-O-tert-butyldimethylsilyl-arabinose

1',2'-dideoxy-1'-β-(5-phenylnaphth-1-yl)-3',5'-bis-O-tert-butyldimethylsilyl-ribose

1'-deoxy-1'-β-(5-phenylnaphth-1-yl)-3',5'-bis-O-tert-butyldimethylsilyl-2'-O-thionocarbonylimidazolyl-arabinose

7-phenyl-1H-phenalen-1-one