tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

Base Information

Chemical Name:tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate
CAS No.:1027702-88-0
Molecular Formula:C₂₉H₃₅FN₂O₂
Molecular Weight:462.608
Hs Code.:

Synonyms:tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

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Chemical Property of tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

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Technology Process of tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

There total 1 articles about tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1027702-88-0
tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

Guidance literature:

Reference yield:

: 1027702-88-0
tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

: 30806-83-8
p-ethoxycarbonylphenyl isocyanate

: 1027703-22-5
4-({[3-({(tert-butoxycarbonyl)[(1R)-1-(1-naphthyl)ethyl]amino}methyl)-4-(3-fluorophenyl)piperidin-1-yl]carbonyl}amino)benzoic acid

Guidance literature:: tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate; p-ethoxycarbonylphenyl isocyanate; With triethylamine; In toluene; at 20 - 100 ℃; for 48h;

With sodium hydroxide; water; In tetrahydrofuran; methanol; at 20 ℃; for 24h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;

Reference yield:

: 1027702-88-0
tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

: 532-55-8
Benzoyl isothiocyanate

: 1027706-69-9
tert-butyl {[1-(aminocarbonothioyl)-3-(3-fluorophenyl)piperidin-4-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate

Guidance literature:: tert-butyl {[4-(3-fluorophenyl)piperidin-3-yl]methyl}[(1R)-1-(1-naphthyl)ethyl]carbamate; Benzoyl isothiocyanate; In toluene; at 20 ℃; for 2h;

With methylamine; In methanol; at 20 ℃; for 48h;