Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine

Base Information

Chemical Name:Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine
CAS No.:212713-08-1
Molecular Formula:C₃₀H₄₆ClO₂P
Molecular Weight:505.121
Hs Code.:
European Community (EC) Number:633-650-4
DSSTox Substance ID:DTXSID20700292
Wikidata:Q82631551
Mol file:212713-08-1.mol

Synonyms:212713-08-1;BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE;chlorobis(3,5-di-tert-butyl-4-methoxyphenyl)phosphine;SCHEMBL459830;Bis(3,5-di-t-butyl-4-methoxyphenyl)chlorophosphine;DTXSID20700292;VOGHMZHRQUWLRE-UHFFFAOYSA-N;MFCD08458881;CS-0108747;FT-0737730;J-013967;Bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphinous chloride

Suppliers and Price of Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine
500mg
$ 236.00

Sigma-Aldrich
Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine
100mg
$ 66.80

American Custom Chemicals Corporation
BIS(3,5-DI-TERT-BUTYL-4-METHOXYPHENYL)CHLOROPHOSPHINE 95.00%
1G
$ 268.80

Alfa Aesar
Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine, 94%
5g
$ 482.00

Alfa Aesar
Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine, 94%
1g
$ 171.00

Total 20 raw suppliers

Chemical Property of Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine

Chemical Property:

Vapor Pressure:1.1E-11mmHg at 25°C
Melting Point:116-120 °C
Boiling Point:552.5°Cat760mmHg
Flash Point:287.9°C
PSA：32.05000
Density:g/cm³
LogP:8.48030
Sensitive.:Air & Moisture Sensitive
Water Solubility.:Reacts with water.
XLogP3:10.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:504.2923954
Heavy Atom Count:34
Complexity:547

Purity/Quality:

97% ^*data from raw suppliers

Bis(3,5-di-tert-butyl-4-methoxyphenyl)chlorophosphine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:F
Statements: 11

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=CC(=CC(=C1OC)C(C)(C)C)P(C2=CC(=C(C(=C2)C(C)(C)C)OC)C(C)(C)C)Cl
Uses It is used as a reactant for asymmetric hydrogenation with iridium catalysts, chemo selective reaction with deprotonated 2-hydoxy-3,3,N-trimethylbutanamide. It is also used as a reactant for synthesis of phosphine- containing amino acids and peptide-based catalyst ligands, nonracemic phosphine-containing amino acids for palladium- catalyzed asymmetric allylic substitution reactions.

Technology Process of Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine

There total 2 articles about Bis(3,5-DI-tert-butyl-4-methoxyphenyl)chlorophosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3,5-di(tert-butyl)-4-methoxyphenylmagnesium bromide

: 212713-08-1
chlorobis(4-methoxy-3,5-di(tert-butyl)phenyl)phosphine

Guidance literature:: 3,5-di(tert-butyl)-4-methoxyphenylmagnesium bromide; With N,N-diethylphosphoramidous dichloride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

With hydrogenchloride; In water; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jo401604n