4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide

Base Information

Chemical Name:4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide
CAS No.:179055-96-0
Molecular Formula:C₁₄H₂₄N₂O₂Si
Molecular Weight:280.442
Hs Code.:
DSSTox Substance ID:DTXSID801151327

Synonyms:4-(tert-butyldimethylsilyloxy)methylbenzhydrazide;179055-96-0;4-{[(tert-butyldimethylsilyl)oxy]methyl}benzohydrazide;4-(((tert-butyldimethylsilyl)oxy)methyl)benzohydrazide;4-[[tert-butyl(dimethyl)silyl]oxymethyl]benzohydrazide;SCHEMBL1312068;MLASCKILMYIEBF-UHFFFAOYSA-N;DTXSID801151327;MFCD18804149;AS-8557;CS-0333814;4-((tert-butyldimethylsilyloxy)methyl)benzohydrazide;4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzoic acid hydrazide

Suppliers and Price of 4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:280.16070455
Heavy Atom Count:19
Complexity:305

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)[Si](C)(C)OCC1=CC=C(C=C1)C(=O)NN

Technology Process of 4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide

There total 5 articles about 4-(Tert-butyldimethylsilyloxy)methylbenzhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 139706-48-2
4-(tert-butyldimethylsilyloxymethyl)benzoic acid methyl ester

: 179055-96-0
4-(((tert-butyldimethylsilyl)oxy)methyl)benzohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; for 1h; Heating;
DOI:10.1021/jm9800853

Reference yield: 67.0%

: 58855-42-8
4-(hydroxymethyl)benzoic hydrazide

: 18162-48-6
tert-butyldimethylsilyl chloride

: 179055-96-0
4-(((tert-butyldimethylsilyl)oxy)methyl)benzohydrazide

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 18h;

Reference yield:

: 6908-41-4,58590-49-1
4-(methoxycarbonyl)benzyl alcohol

: 179055-96-0
4-(((tert-butyldimethylsilyl)oxy)methyl)benzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / imidazole / dimethylformamide / 1.5 h / Ambient temperature

2: 100 percent / H₂NNH₂*H₂O / ethanol / 1 h / Heating

With 1H-imidazole; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9800853