N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Base Information

Chemical Name:N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
CAS No.:1131010-46-2
Molecular Formula:C₂₈H₂₄Cl₃N₃O₃
Molecular Weight:556.876
Hs Code.:

Synonyms:N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

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Technology Process of N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

There total 1 articles about N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 60425-49-2
(+)-α-amino-4-phenylbutyric acid methyl ester hydrochloride

: 168273-05-0
5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbonyl chloride

: 1131010-46-2
N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

Reference yield: 95.0%

: 1131010-46-2
N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide

: 1131010-47-3
C₂₇H₂₂Cl₃N₃O₃

Guidance literature:: N-(homophenylalanine methyl ester)-1-(2,4-dichloropheny)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 5h;

With hydrogenchloride; In tetrahydrofuran; water; pH=~ 1 - 2;