BOC-D-GLN(TRT)-OH

Base Information

• Chemical Name: BOC-D-GLN(TRT)-OH
• CAS No.: 210750-95-1
• Molecular Formula: C₂₉H₃₂N₂O₅
• Molecular Weight: 488.583
• Mol file: 210750-95-1.mol

Synonyms:N-ALPHA-T-BOC-GAMMA-TRITYL-D-GLUTAMINE;N-ALPHA-T-BUTOXYCARBONYL-N-GAMMA-TRITYL-D-GLUTAMINE;BOC-N-DELTA-TRITYL-D-GLUTAMINE;BOC-D-GLN(TRT)-OH;BOC-D-TRITYL GLUTAMINE

Chemical Property of BOC-D-GLN(TRT)-OH

Chemical Property:

• Boiling Point: 728.9±60.0 °C(Predicted)
• PKA: 3.84±0.10(Predicted)
• PSA: 104.73000
• Density: 1.188±0.06 g/cm3(Predicted)
• LogP: 5.63460
• Storage Temp.: Store at RT.

Purity/Quality:

98%,99%, ^*data from raw suppliers

Boc-D-Gln(Trt)-OH 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BOC-D-GLN(TRT)-OH

There total 6 articles about BOC-D-GLN(TRT)-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

triphenylmethyl alcohol (76-84-6) → Boc-L-Gln(Trt)-OH (132388-69-3,210750-95-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / Ac₂O, conc.H₂SO₄ / acetic acid / 60 °C

With sulfuric acid; acetic anhydride; In acetic acid;

DOI:10.1016/S0040-4039(00)74872-6

Reference yield:

(S)-2-(((benzyloxy)carbonyl)amino)-5-oxo-5-(tritylamino)pentanoic acid (132388-60-4,200625-96-3) → Boc-L-Gln(Trt)-OH (132388-69-3,210750-95-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / H₂, 1N HCl / 10percent Pd-C / methanol; H₂O / 1 h

With hydrogenchloride; hydrogen; palladium on activated charcoal; In methanol; water;

DOI:10.1016/S0040-4039(00)74872-6

Reference yield:

L-glutamine (56-85-9,26700-71-0) → Boc-L-Gln(Trt)-OH (132388-69-3,210750-95-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 35 percent / Ac₂O, conc.H₂SO₄ / acetic acid / 60 °C

With sulfuric acid; acetic anhydride; In acetic acid;

DOI:10.1016/S0040-4039(00)74872-6

upstream raw materials:

di-tert-butyl dicarbonate

5-trityl-L-glutamine

triphenylmethyl alcohol

L-glutamine

Downstream raw materials:

tert-butyl (1-(4-cyanophenyl)-4-oxo-4-(tritylamino)butyl)carbamate

fellutamide B