3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid

Base Information

• Chemical Name: 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid
• CAS No.: 341556-94-3
• Molecular Formula: C₁₄H₁₄O₆
• Molecular Weight: 278.262
• Mol file: 341556-94-3.mol

Synonyms:3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid

Chemical Property of 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid

There total 3 articles about 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

malonic acid (141-82-2) + 2,3-dimethoxy-1,4-benzenedicarboxaldehyde (179693-85-7) → 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid (341556-94-3)

Guidance literature:

With piperidine; pyridine; for 24h; Heating;

DOI:10.1021/jm000107x

Reference yield:

piperidine (110-89-4) + 2,3-dimethoxy-1,4-benzenedicarboxaldehyde (179693-85-7) → 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid (341556-94-3)

Guidance literature:

With pyridine; malonic acid;

Reference yield:

dimethyl 2,3-dimethoxyterephthalate (7168-94-7) → 3,3'-(2,3-dimethoxy-1,4-phenylene)bisacrylic acid (341556-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / N-methylpiperazine; sodium bis(methoxyethoxy)aluminum hydride / toluene / 0.17 h / -20 °C

2: 93 percent / pyridine; piperidine / 24 h / Heating

With piperidine; 1-methyl-piperazine; pyridine; sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; 2: Doebner reaction;

DOI:10.1021/jm000107x

upstream raw materials:

malonic acid

2,3-dimethoxy-1,4-benzenedicarboxaldehyde

dimethyl 2,3-dimethoxyterephthalate

piperidine