4-Amino-5-chloro-2-methoxybenzoic acid

Base Information

• Chemical Name: 4-Amino-5-chloro-2-methoxybenzoic acid
• CAS No.: 21386-95-8
• Molecular Formula: C7H6 Cl N O3
• Molecular Weight: 187.58
• Hs Code.: 2922509090
• Mol file: 21386-95-8.mol

Synonyms:Salicylicacid, 4-amino-5-chloro- (8CI); 2-Hydroxy-4-amino-5-chlorobenzoic acid

Chemical Property of 4-Amino-5-chloro-2-methoxybenzoic acid

Chemical Property:

• PSA: 72.55000
• LogP: 2.21020

Purity/Quality:

99% ^*data from raw suppliers

4-Amino-5-chloro-2-hydroxy-benzoicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Amino-5-chloro-2-methoxybenzoic acid

There total 3 articles about 4-Amino-5-chloro-2-methoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-amino-5-chloro-2-methoxybenzoate (20896-27-9) → 4-amino-5-chloro-2-hydroxybenzoic acid (21386-95-8)

Guidance literature:

With sodium hydroxide; boron tribromide; In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane;

Reference yield:

methyl 2-methoxy-5-chloro-4-aminobenzoate hydrochloride (130312-40-2) → 4-amino-5-chloro-2-hydroxybenzoic acid (21386-95-8)

Guidance literature:

With hydrogenchloride; boron tribromide; In sodium hydroxide; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; dichloromethane;

Reference yield:

→ 4-amino-5-chloro-2-hydroxybenzoic acid (21386-95-8)

Guidance literature:

Na-Salz v. 4-Chlor-3-amino-phenol, 1.) CO2, Autoklav, 2.) HCl aq., 3.) NaHCO3;

upstream raw materials:

methyl 4-amino-5-chloro-2-methoxybenzoate

methyl 2-methoxy-5-chloro-4-aminobenzoate hydrochloride

Downstream raw materials:

5-Chloro-4-(2-propenylamino)-2-(2-propenyloxy)benzoic acid

4-amino-5-chloro-2-hydroxybenzoic acid,methyl ester