4-(Trifluoromethyl)benzoic anhydride

Base Information

Chemical Name:4-(Trifluoromethyl)benzoic anhydride
CAS No.:25753-16-6
Molecular Formula:C16H8 F6 O3
Molecular Weight:362.228
Hs Code.:2916399090
European Community (EC) Number:670-955-1
DSSTox Substance ID:DTXSID80375329
Nikkaji Number:J1.685.412C
Wikidata:Q72511700
Mol file:25753-16-6.mol

Synonyms:4-(Trifluoromethyl)benzoic anhydride;25753-16-6;TFBA;[4-(trifluoromethyl)benzoyl] 4-(trifluoromethyl)benzoate;4-Trifluoromethylbenzoic Anhydride;Benzoic acid, 4-(trifluoromethyl)-, anhydride;SCHEMBL779219;4-(trifluoromethyl)benzoyl 4-(trifluoromethyl)benzoate;DTXSID80375329;FNAWJOBKLWLHTA-UHFFFAOYSA-N;4-(Trifluoromethyl)benzoicanhydride;MFCD00671577;AKOS005256835;p-trifluoromethylbenzoic acid anhydride;AS-62706;Bis(4-trifluoromethylbenzoic acid)anhydride;FT-0638547;T1593;D92491;A817997;J-513919;[4-(trifluoromethyl)phenyl]carbonyl 4-(trifluoromethyl)benzoate;4-(trifluoromethyl)benzoic acid [oxo-[4-(trifluoromethyl)phenyl]methyl] ester

Suppliers and Price of 4-(Trifluoromethyl)benzoic anhydride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Trifluoromethylbenzoic Anhydride
1g
$ 75.00

TCI Chemical
4-Trifluoromethylbenzoic Anhydride >97.0%(GC)(T)
10g
$ 186.00

Matrix Scientific
4-(Trifluoromethyl)benzoic anhydride
1g
$ 32.00

Matrix Scientific
4-(Trifluoromethyl)benzoic anhydride
5g
$ 98.00

Crysdot
4-Trifluoromethylbenzoic Anhydride 97%
25g
$ 514.00

Chem-Impex
4-Trifluoromethylbenzoicanhydride,≥97%(Assaybytitration,GC) ≥97%(Assaybytitration,GC)
5G
$ 104.83

Chem-Impex
4-Trifluoromethylbenzoicanhydride,97%(Assaybytitration,GC) 97%(Assaybytitration,GC)
1G
$ 33.60

Chem-Impex
4-Trifluoromethylbenzoicanhydride,≥97%(Assaybytitration,GC) ≥97%(Assaybytitration,GC)
250MG
$ 17.47

Chem-Impex
4-Trifluoromethylbenzoicanhydride,97%(Assaybytitration,GC) 97%(Assaybytitration,GC)
25G
$ 459.20

Chemenu
4-Trifluoromethylbenzoic Anhydride 95+%
10g
$ 252.00

Total 33 raw suppliers

Chemical Property of 4-(Trifluoromethyl)benzoic anhydride

Chemical Property:

Vapor Pressure:2.61E-06mmHg at 25°C
Melting Point:130 °C
Refractive Index:1.486
Boiling Point:390.6°Cat760mmHg
Flash Point:183.5°C
PSA：43.37000
Density:1.427g/cm³
LogP:4.72140
Storage Temp.:Inert atmosphere,Room Temperature
Sensitive.:Moisture Sensitive
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:362.03776309
Heavy Atom Count:25
Complexity:439

Purity/Quality:

97% ^*data from raw suppliers

4-Trifluoromethylbenzoic Anhydride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)OC(=O)C2=CC=C(C=C2)C(F)(F)F)C(F)(F)F

Technology Process of 4-(Trifluoromethyl)benzoic anhydride

There total 5 articles about 4-(Trifluoromethyl)benzoic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 455-24-3
4-trifluoromethylbenzoic acid

: 25753-16-6
4-(trifluoromethyl)benzoic anhydride

Guidance literature:: With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;
DOI:10.1039/c8ob00178b

Reference yield: 89.0%

: 455-24-3
4-trifluoromethylbenzoic acid

: 329-15-7
4-trifluoromethyl-phenyl acetyl chloride

: 25753-16-6
4-(trifluoromethyl)benzoic anhydride

Guidance literature:: With pyridine; In dichloromethane; for 21h; Ambient temperature;
DOI:10.1246/bcsj.66.1516 DOI:10.1246/bcsj.66.3729

Reference yield: 57.6%

: 1-(4-(trifluoromethyl)benzoyl)piperidine-2,6-dione

: 25753-16-6
4-(trifluoromethyl)benzoic anhydride

Guidance literature:: With water; scandium tris(trifluoromethanesulfonate); In benzene; at 120 ℃; for 18h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c7ob00086c