(10-Hydroxydecyl)-triohenylphosphonium-bromid

Base Information

• Chemical Name: (10-Hydroxydecyl)-triohenylphosphonium-bromid
• CAS No.: 64417-10-3
• Molecular Formula: Br*C₂₈H₃₆OP
• Molecular Weight: 499.471
• Mol file: 64417-10-3.mol

Synonyms:(10-Hydroxydecyl)-triohenylphosphonium-bromid

Chemical Property of (10-Hydroxydecyl)-triohenylphosphonium-bromid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (10-Hydroxydecyl)-triohenylphosphonium-bromid

There total 5 articles about (10-Hydroxydecyl)-triohenylphosphonium-bromid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-bromo-10-decanol (53463-68-6) + triphenylphosphine (603-35-0) → (10-Hydroxydecyl)-triohenylphosphonium-bromid (64417-10-3)

Guidance literature:

In acetonitrile; at 120 ℃; for 0.0833333h; Flow reactor;

DOI:10.1039/d0md00153h

Reference yield: 72.0%

1-bromo-10-decanol (53463-68-6) → (10-Hydroxydecyl)-triohenylphosphonium-bromid (64417-10-3)

Guidance literature:

With triphenylphosphine; In acetonitrile; for 90h; Reflux;

DOI:10.1021/tx300315h

Reference yield: 71.0%

1-bromo-10-(tetrahydropyranyloxy)decane (51795-88-1) + triphenylphosphine (603-35-0) → (10-Hydroxydecyl)-triohenylphosphonium-bromid (64417-10-3)

Guidance literature:

In acetonitrile; for 48h; Heating;

DOI:10.1039/b504889c

upstream raw materials:

1-bromo-10-decanol

triphenylphosphine

1-bromo-10-(tetrahydropyranyloxy)decane

1,10-Decanediol

Downstream raw materials:

Δ10-hexadecenol

C₃₄H₅₆O₂Si

C₃₄H₅₄O₂Si

(10-bromodecyl)triphenylphosphonium bromide

Refernces

• 1、 Aguilera, Jocelyn,Castro-Castillo, Vicente,Ferreira, Jorge,Gajardo-De La Fuente, Javier,Olmedo, Ivonne,Palominos, Charlotte,Ramires-Fernandez, Ricardo,Valencia, Marcelo,Catalán, Mabel,Domínguez, Marta,Jara, José A.,Molina-Berríos, Alfredo,Souto, José A.. "Continuous flow synthesis of lipophilic cations derived from benzoic acid as new cytotoxic chemical entities in human head and neck carcinoma cell lines". . p. 1210 - 1225. Retrieved 2020/11/03.
• 2、 Castro-Castillo, Vicente,Catalán, Mabel,Ferreira, Jorge,Fuentes-Retamal, Sebastián,Jara, José Antonio,Maya, Juan Diego,Parra, Eduardo,Pavani, Mario,Rojas, Diego,Sandoval-Acu?a, Cristian. "Novel benzoate-lipophilic cations selectively induce cell death in human colorectal cancer cell lines". . . Retrieved 2020/03/06.