N-(2-chloro-6-methylphenyl)acetamide

Base Information

Chemical Name:N-(2-chloro-6-methylphenyl)acetamide
CAS No.:21352-09-0
Molecular Formula:C9H10 Cl N O
Molecular Weight:183.637
Hs Code.:2924299090
DSSTox Substance ID:DTXSID60401019
Nikkaji Number:J491.062A
Wikidata:Q82204085
Mol file:21352-09-0.mol

Synonyms:N-(2-chloro-6-methylphenyl)acetamide;21352-09-0;2-CHLORO-6-METHYLACETANILINE;2-Chloro-6-methylacetanilin;2'-Chloro-6'-methylacetanilide;o-Acetotoluidide, 6'-chloro-;3-chloro-2-acetylaminotoluene;SCHEMBL2921682;DTXSID60401019;VFGNPYWQUOSOSR-UHFFFAOYSA-N;AKOS003107812;N-(6-chloro-2-methyl-phenyl)-acetamide;CS-0017716

Suppliers and Price of N-(2-chloro-6-methylphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-6-methylacetanilin
2mg
$ 60.00

American Custom Chemicals Corporation
2-CHLORO-6-METHYLACETANILIN 95.00%
5MG
$ 497.21

Total 8 raw suppliers

Chemical Property of N-(2-chloro-6-methylphenyl)acetamide

Chemical Property:

PSA：29.10000
LogP:2.67980
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:183.0450916
Heavy Atom Count:12
Complexity:172

Purity/Quality:

96% ^*data from raw suppliers

2-Chloro-6-methylacetanilin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)Cl)NC(=O)C
Uses 2-Chloro-6-methylacetanilin (cas# 21352-09-0) is a useful reagent for electrophilic substitution of 2'',4''- and 2'',6''-dihaloacetanilides.

Technology Process of N-(2-chloro-6-methylphenyl)acetamide

There total 13 articles about N-(2-chloro-6-methylphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.7%

: 120-66-1
N-(2-methylphenyl)acetamide

: 5202-86-8
4-chloro-2-methylacetanilide

: 21352-09-0
N-(6-chloro-2-methylphenyl)acetamide

Guidance literature:: With 1,3-di(adamantan-1-yl)-1H-imidazol-3-ium tetrafluoroborate; N-chloro-succinimide; camphor-10-sulfonic acid; In 1,4-dioxane; at 25 ℃; for 24h;
DOI:10.1055/s-0035-1560376

Reference yield: 74.0%

: 70786-65-1
N-ethanoyl-2-methylphenylhydroxyamine

: 21352-09-0
N-(6-chloro-2-methylphenyl)acetamide

Guidance literature:: With thionyl chloride; In diethyl ether; for 1h; T < 5 deg C;

Reference yield: 66.0%

: 120-66-1
N-(2-methylphenyl)acetamide

: 21352-09-0
N-(6-chloro-2-methylphenyl)acetamide

Guidance literature:: With N-chloro-succinimide; cobalt acetylacetonate; trifluoroacetic acid; silver(l) oxide; In 1,2-dichloro-ethane; at 60 ℃; for 16h; regioselective reaction;
DOI:10.1039/c8ob01448e