70786-65-1Relevant articles and documents
Catalyst-free generation of acyl radicals induced by visible light in water to construct C-N bonds
Ran, Maogang,He, Jiaxin,Yan, Boyu,Liu, Wenbo,Li, Yi,Fu, Yunfen,Li, Chao-Jun,Yao, Qiuli
supporting information, p. 1970 - 1975 (2021/03/16)
We describe herein a catalyst-free and redox-neutral photochemical strategy for the direct generation of acyl radicals from α-diketones, and its selective conversion of nitrosoarenes to hydroxyamides or amides with AcOH or NaCl as an additive. The reaction was carried out under mild conditions in water with purple LEDs as the light source. A broad scope of substrates was demonstrated. Mechanistic experiments indicate that α-diketones cleave to give acyl radicals, with hydroxyamides being further reduced to amides.
Hydroxamic Acids as Chemoselective (ortho-Amino)arylation Reagents via Sigmatropic Rearrangement
Shaaban, Saad,Tona, Veronica,Peng, Bo,Maulide, Nuno
supporting information, p. 10938 - 10941 (2017/08/30)
The use of readily available hydroxamic acids as reagents for the chemoselective (ortho-amino)arylation of amides is described. This reaction proceeds under metal-free, mild conditions, displays a very broad scope, and constitutes a direct approach for the metal-free attachment of aniline residues to carbonyl derivatives.
A Direct Aromatic Methylsulfanylation of N-Aryl-N-methoxyacetamides with an Aluminium Chloride-Dimethyl Sulfide System
Matsumoto, Kazuhiro,Kato, Miyako,Sakamoto, Takeshi,Kikugawa, Yasuo
, p. 34 - 35 (2007/10/03)
Treatment of N-aryl-N-methoxyacetamides, which bear a strong electron-donating group on the aryl ring, with an AlCl3-Me2S system results in heterocyclic cleavage of the nitrogen-oxygen bond and introduction of a methylsulfanyl group at the ortho or para position of the aryl ring.
