Technology Process of C22H25F4N5O5S
There total 8 articles about C22H25F4N5O5S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 6 steps
1.1: 8-quinolinol; copper(l) iodide; potassium carbonate / dimethyl sulfoxide / 135 °C
2.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
2.2: 1 h / -78 °C
3.1: sodium hydride / 1-methyl-pyrrolidin-2-one / 3 h / 0 - 100 °C / Inert atmosphere
4.1: iron; hydrogenchloride / ethanol; water / 0.33 h / 80 °C
5.1: trimethylaluminum / 1,2-dichloro-ethane; toluene / 2 h / 0 - 20 °C
6.1: triethylamine / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; copper(l) iodide; 8-quinolinol; trimethylaluminum; iron; sodium hydride; potassium carbonate; triethylamine; lithium hexamethyldisilazane;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; ethanol; dichloromethane; water; dimethyl sulfoxide; 1,2-dichloro-ethane; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: iron; hydrogenchloride / ethanol; water / 0.33 h / 80 °C
2: trimethylaluminum / 1,2-dichloro-ethane; toluene / 2 h / 0 - 20 °C
3: triethylamine / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; trimethylaluminum; iron; triethylamine;
In
ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / 1-methyl-pyrrolidin-2-one / 3 h / 0 - 100 °C / Inert atmosphere
2: iron; hydrogenchloride / ethanol; water / 0.33 h / 80 °C
3: trimethylaluminum / 1,2-dichloro-ethane; toluene / 2 h / 0 - 20 °C
4: triethylamine / dichloromethane / 2 h / 20 °C
With
hydrogenchloride; trimethylaluminum; iron; sodium hydride; triethylamine;
In
1-methyl-pyrrolidin-2-one; ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene;