6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene

Base Information

• Chemical Name: 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene
• CAS No.: 884324-38-3
• Molecular Formula: C₄₀H₅₂O₅Si₂
• Molecular Weight: 669.021
• Mol file: 884324-38-3.mol

Synonyms:6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene

Chemical Property of 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene

There total 3 articles about 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(6,6,8,8-tetraisopropyl-10H-5,7,9-trioxa-6,8-disila-benzocycloocten-2-yl)-methanol (884324-37-2) + mono-4-methoxytrityl chloride (14470-28-1) → 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene (884324-38-3)

Guidance literature:

With pyridine; at 20 ℃; for 4.5h;

DOI:10.1016/j.tetlet.2006.01.135

Reference yield:

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane (69304-37-6) → 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene (884324-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Et₃N / tetrahydrofuran / 3 h / 20 °C

2: 89 percent / pyridine / 4.5 h / 20 °C

With pyridine; triethylamine; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.01.135

Reference yield:

2,4-bis(hydroxymethyl)phenol (2937-60-2) → 6,6,8,8-tetraisopropyl-2-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-10H-5,7,9-trioxa-6,8-disila-benzocyclooctene (884324-38-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / Et₃N / tetrahydrofuran / 3 h / 20 °C

2: 89 percent / pyridine / 4.5 h / 20 °C

With pyridine; triethylamine; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.01.135

upstream raw materials:

(6,6,8,8-tetraisopropyl-10H-5,7,9-trioxa-6,8-disila-benzocycloocten-2-yl)-methanol

mono-4-methoxytrityl chloride

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

2,4-bis(hydroxymethyl)phenol

Downstream raw materials:

2-azidomethyl-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-phenol

pentanedioic acid mono-{2-azidomethyl-4-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-phenyl} ester