C₁₇H₂₃NO₄

Base Information

• Chemical Name: C₁₇H₂₃NO₄
• CAS No.: 955124-13-7
• Molecular Formula: C₁₇H₂₃NO₄
• Molecular Weight: 305.374
• Mol file: 955124-13-7.mol

Synonyms:C₁₇H₂₃NO₄

Chemical Property of C₁₇H₂₃NO₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₇H₂₃NO₄

There total 4 articles about C₁₇H₂₃NO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) + tert-butyl (formylmethyl)(phenyl)carbamate (141222-95-9) → C17H23NO4 (955124-13-7)

Guidance literature:

diethoxyphosphoryl-acetic acid ethyl ester; With 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In acetonitrile; at 20 ℃; for 0.333333h;

tert-butyl (formylmethyl)(phenyl)carbamate; In acetonitrile; at 0 ℃; for 1.5h; Further stages.;

DOI:10.1021/jo071124y

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C17H23NO4 (955124-13-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 94 percent / dioxane / 36 h / 50 °C

2.1: 94 percent / oxalyl chloride; DMSO; iPr₂NEt / CH₂Cl₂ / -60 - 0 °C

3.1: DBU; LiCl / acetonitrile / 0.33 h / 20 °C

3.2: 75 percent / acetonitrile / 1.5 h / 0 °C

With oxalyl dichloride; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; lithium chloride; In 1,4-dioxane; dichloromethane; acetonitrile; 2.1: Swern oxidation;

DOI:10.1021/jo071124y

Reference yield:

N-phenyl-N-(tert-butoxtcarbonyl)-2-aminoethanol (121492-10-2) → C17H23NO4 (955124-13-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 94 percent / oxalyl chloride; DMSO; iPr₂NEt / CH₂Cl₂ / -60 - 0 °C

2.1: DBU; LiCl / acetonitrile / 0.33 h / 20 °C

2.2: 75 percent / acetonitrile / 1.5 h / 0 °C

With oxalyl dichloride; dimethyl sulfoxide; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; lithium chloride; In dichloromethane; acetonitrile; 1.1: Swern oxidation;

DOI:10.1021/jo071124y

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

tert-butyl (formylmethyl)(phenyl)carbamate

di-tert-butyl dicarbonate

N-phenyl-N-(tert-butoxtcarbonyl)-2-aminoethanol

Downstream raw materials:

4-anilinocrotonic acid ethyl ester