4-Bromoquinoline-2-carboxylic acid

Base Information

Chemical Name:4-Bromoquinoline-2-carboxylic acid
CAS No.:209003-46-3
Molecular Formula:C10H6 Br N O2
Molecular Weight:252.067
Hs Code.:2933499090
DSSTox Substance ID:DTXSID90573718
Nikkaji Number:J1.526.743G
Wikidata:Q82462526
Mol file:209003-46-3.mol

Synonyms:4-bromoquinoline-2-carboxylic acid;209003-46-3;2-Quinolinecarboxylic acid, 4-bromo-;MFCD08705670;SCHEMBL837668;DTXSID90573718;DLAHQKXVDUYPHR-UHFFFAOYSA-N;AKOS015966898;SB71584;AS-62585;SY105773;4-Bromo-2-quinolinecarboxylic acid, AldrichCPR;C73945;EN300-3539269;A879358

Suppliers and Price of 4-Bromoquinoline-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
4-bromoquinoline-2-carboxylicacid 95
1g
$ 500.00

Crysdot
4-Bromoquinoline-2-carboxylicacid 97%
1g
$ 289.00

Chemenu
4-bromoquinoline-2-carboxylicacid 97%
1g
$ 273.00

Chemenu
4-bromoquinoline-2-carboxylicacid 97%
5g
$ 1092.00

American Custom Chemicals Corporation
4-BROMOQUINOLINE-2-CARBOXYLIC ACID 95.00%
1G
$ 909.56

AK Scientific
4-Bromoquinoline-2-carboxylicacid
5g
$ 1627.00

Total 25 raw suppliers

Chemical Property of 4-Bromoquinoline-2-carboxylic acid

Chemical Property:

Vapor Pressure:4.71E-07mmHg at 25°C
Melting Point:159-164 °C (decomp)
Refractive Index:1.709
Boiling Point:398.1°Cat760mmHg
PKA:3?+-.0.50(Predicted)
Flash Point:194.6°C
PSA：50.19000
Density:1.732g/cm³
LogP:2.69550
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:250.95819
Heavy Atom Count:14
Complexity:234

Purity/Quality:

97% ^*data from raw suppliers

4-bromoquinoline-2-carboxylicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC(=N2)C(=O)O)Br

Technology Process of 4-Bromoquinoline-2-carboxylic acid

There total 1 articles about 4-Bromoquinoline-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24782-43-2
ethyl 4-hydroxyquinoline-2-carboxylate

: 209003-46-3
4-bromoquinoline-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: PBr₅ / 120 °C

2: aqueous NaOH

With sodium hydroxide; phosphorus pentabromide;
DOI:10.1021/jo01167a014

Reference yield: 95.0%

: 209003-46-3
4-bromoquinoline-2-carboxylic acid

: 931-15-7,931-16-8,6850-38-0,6982-39-4,33092-82-9,38898-70-3,74111-21-0,108267-20-5
(1S,2S)-trans-2-aminocyclohexanol

: 1314141-23-5
4-bromo-N-[(1S,2S)-2-hydroxycyclohexyl]quinoline-2-carboxamide

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane; at 20 ℃; for 16h;

Reference yield:

: 209003-46-3
4-bromoquinoline-2-carboxylic acid

: 1244016-75-8
4-(4-((4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)phenyl)ethynyl)benzyl)morpholine

: C₂₉H₂₄N₂O₃

Guidance literature:: With caesium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In water; acetonitrile; at 60 ℃; for 2h; Inert atmosphere;