3-(3-chlorophenyl)-1H-pyrazol-5-amine

Base Information

Chemical Name:3-(3-chlorophenyl)-1H-pyrazol-5-amine
CAS No.:208519-09-9
Molecular Formula:C9H8 Cl N3
Molecular Weight:193.636
Hs Code.:2933199090
European Community (EC) Number:819-600-6
DSSTox Substance ID:DTXSID80396872
Wikidata:Q82197807
Mol file:208519-09-9.mol

Synonyms:3-(3-chlorophenyl)-1H-pyrazol-5-amine;208519-09-9;5-(3-chlorophenyl)-1H-pyrazol-3-amine;1H-Pyrazol-3-amine, 5-(3-chlorophenyl)-;5-AMINO-3-(3-CHLOROPHENYL)PYRAZOLE;5-(3-Chloro-phenyl)-2H-pyrazol-3-ylamine;MFCD02664265;3-(3-chlorophenyl)-1H-pyrazol-5-amine, AldrichCPR;3-Amino-5-(3-chlorophenyl)-1H-pyrazole;SCHEMBL461187;2-Bromo-5-methoxybenzonitrile;DTXSID80396872;HLKDVENNWRMMOS-UHFFFAOYSA-N;HMS3446A04;AC5445;BBL020224;STK889348;AKOS000181877;AKOS004912490;AA-0869;AB12106;CCG-139765;SY012512;5-Amino-3-(3-chlorophenyl)-1H-pyrazole;BB 0249379;CS-0146991;FT-0604336;EN300-53483;J-510600;F3379-0346;Z317042240

Suppliers and Price of 3-(3-chlorophenyl)-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(3-Chlorophenyl)-1h-pyrazol-5-amine
100mg
$ 45.00

SynQuest Laboratories
5-Amino-3-(3-chlorophenyl)-1H-pyrazole
1 g
$ 53.00

SynQuest Laboratories
5-Amino-3-(3-chlorophenyl)-1H-pyrazole
5 g
$ 159.00

Sigma-Aldrich
3-(3-Chlorophenyl)-1H-pyrazol-5-amine Aldrich
1g
$ 144.00

Matrix Scientific
3-(3-Chlorophenyl)-1H-pyrazol-5-amine
500mg
$ 200.00

Labseeker
3-(3-chlorophenyl)-1H-pyrazol-5-aminehydrochloride 95
25g
$ 3117.00

Crysdot
3-(3-Chlorophenyl)-1H-pyrazol-5-amine 95+%
250mg
$ 65.00

Crysdot
3-(3-Chlorophenyl)-1H-pyrazol-5-amine 95+%
1g
$ 160.00

CHESS?
KP001298:5-(3-Chloro-phenyl)-2H-pyrazol-3-ylamine 98
5 g
$ 1020.00

CHESS?
KP001298:5-(3-Chloro-phenyl)-2H-pyrazol-3-ylamine 98
1 g
$ 336.00

Total 23 raw suppliers

Chemical Property of 3-(3-chlorophenyl)-1H-pyrazol-5-amine

Chemical Property:

Vapor Pressure:5.69E-09mmHg at 25°C
Melting Point:138-140°C
Refractive Index:1.67
Boiling Point:469.1°C at 760 mmHg
Flash Point:237.5°C
PSA：54.70000
Density:1.378g/cm³
LogP:2.89350
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:193.0406750
Heavy Atom Count:13
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

3-(3-Chlorophenyl)-1h-pyrazol-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)C2=CC(=NN2)N

Technology Process of 3-(3-chlorophenyl)-1H-pyrazol-5-amine

There total 2 articles about 3-(3-chlorophenyl)-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 21667-62-9
3-chlorobenzoylacetonitrile

: 208519-09-9
5-(3-chlorophenyl)-1H-pyrazole-3-amine

Guidance literature:: With hydrazine hydrate; In methanol; at 150 ℃; for 0.0833333h; Microwave irradiation;
DOI:10.3762/bjoc.14.104

Reference yield:

: 2905-65-9
methyl 3-chlorobenzoate

: 208519-09-9
5-(3-chlorophenyl)-1H-pyrazole-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropylamide / tetrahydrofuran / -78 °C

1.2: tetrahydrofuran / -78 - 20 °C

2.1: hydrazine monohydrate / ethanol / 5 h / Heating

With hydrazine hydrate; lithium diisopropyl amide; In tetrahydrofuran; ethanol;
DOI:10.1016/j.bmc.2006.07.023