2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole

Base Information

• Chemical Name: 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole
• CAS No.: 111122-90-8
• Molecular Formula: C₂₁H₁₈O₃S
• Molecular Weight: 350.438
• Mol file: 111122-90-8.mol

Synonyms:2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole

Chemical Property of 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole

There total 2 articles about 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-phenyl-1,3-benzoxathiolium tetrafluoroborate (58948-35-9) + 1,3-Dimethoxybenzene (151-10-0) → 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole (111122-90-8)

Guidance literature:

With pyridine; In acetonitrile; at 50 ℃; for 2h;

DOI:10.1055/s-1987-27931

Reference yield:

1,3-Dimethyl-2-(2-phenyl-benzo[1,3]oxathiol-2-yl)-1H-indole (111123-04-7) → 2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole (111122-90-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrafluoroboric acid/ether complex / acetonitrile

2: 83 percent / pyridine / acetonitrile / 2 h / 50 °C

With pyridine; tetrafluoroboric acid; diethyl ether; In acetonitrile;

DOI:10.1055/s-1987-27931

Reference yield: 95.0%

2-(2,4-Dimethoxy-phenyl)-2-phenyl-benzo[1,3]oxathiole (111122-90-8) → 2,4-dimethoxybenzophenone (3555-84-8)

Guidance literature:

With tetrafluoroboric acid; mercury(II) oxide; In tetrahydrofuran; Ambient temperature;

DOI:10.1055/s-1987-27931

upstream raw materials:

2-phenyl-1,3-benzoxathiolium tetrafluoroborate

1,3-Dimethoxybenzene

1,3-Dimethyl-2-(2-phenyl-benzo[1,3]oxathiol-2-yl)-1H-indole

Downstream raw materials:

2,4-dimethoxybenzophenone

2-phenyl-1,3-benzoxathiolium tetrafluoroborate

1,3-Dimethoxybenzene

phenyl(1H-pyrrol-2-yl)methanone

Refernces