Triethoxy(4-methoxyphenyl)silane

Base Information

• Chemical Name: Triethoxy(4-methoxyphenyl)silane
• CAS No.: 21130-91-6
• Molecular Formula: C13H22 O4 Si
• Molecular Weight: 270.401
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID30458070
• Nikkaji Number: J918.720K
• Mol file: 21130-91-6.mol

Synonyms:Triethoxy(4-methoxyphenyl)silane;21130-91-6;Triethoxy-(4-methoxyphenyl)silane;p-methoxyphenyltriethoxysilane;4-Methoxyphenyltriethoxysilane;TRIETHOXY(4-METHOXYPHENYL)SILANE 97;C13H22O4Si;SCHEMBL2452802;DTXSID30458070;MFCD05665142;AKOS015916736;Triethoxy(4-methoxyphenyl)silane, 97%;AS-82627;TRIETHOXY(4-METHOXYPHENYL)SILANE 97;E79412;J-013868

Chemical Property of Triethoxy(4-methoxyphenyl)silane

Chemical Property:

• Vapor Pressure: 0.00489mmHg at 25°C
• Refractive Index: n20/D 1.474(lit.)
• Boiling Point: 128 °C3 mm Hg(lit.)
• Flash Point: 110 °C
• PSA: 36.92000
• Density: 1.030 g/mL at 25 °C(lit.)
• LogP: 1.95060
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 270.12873571
• Heavy Atom Count: 18
• Complexity: 200

Purity/Quality:

99.5% ^*data from raw suppliers

Triethoxy(4-methoxyphenyl)silane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCO[Si](C1=CC=C(C=C1)OC)(OCC)OCC
• Uses: A silicon-based nucleophile shown to be reactive in Pd-catalyzed cross-coupling reactions.

Technology Process of Triethoxy(4-methoxyphenyl)silane

There total 10 articles about Triethoxy(4-methoxyphenyl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Triethoxysilane (998-30-1) + para-iodoanisole (696-62-8) → triethoxy(4-methoxyphenyl)silane (21130-91-6) + methoxybenzene (100-66-3)

Guidance literature:

With triethylamine; bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1016/j.tet.2007.02.103

Reference yield: 90.0%

Triethoxysilane (998-30-1) + para-iodoanisole (696-62-8) → triethoxy(4-methoxyphenyl)silane (21130-91-6)

Guidance literature:

With bis(acetonitrile)(1,5-cyclooctadiene)rhodium(I) tetrafluoroborate; triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1021/ol025770p

Reference yield: 90.0%

4-methoxybenzenediazonium 4-methylbenzenesulfonate (123155-78-2) + Triethoxysilane (998-30-1) → triethoxy(4-methoxyphenyl)silane (21130-91-6)

Guidance literature:

4-methoxybenzenediazonium 4-methylbenzenesulfonate; With chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetra-(n-butyl)ammonium iodide; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 2h; Inert atmosphere;

Triethoxysilane; In N,N-dimethyl-formamide; at 20 - 100 ℃; Inert atmosphere;

DOI:10.1055/s-0029-1219090

upstream raw materials:

Triethoxysilane

para-iodoanisole

1-bromo-4-methoxy-benzene

tetraethoxy orthosilicate

Downstream raw materials:

4,4'-Dimethoxybiphenyl

3-(4-methoxyphenyl)cyclohexene

1-(4'-methoxy-biphenyl-4-yl)-ethanone

(E)-3-(4-methoxyphenyl)acrylic acid butyl ester