p-Nitrophenylphosphorylcholine

Base Information

Chemical Name:p-Nitrophenylphosphorylcholine
CAS No.:21064-69-7
Molecular Formula:C11H17 N2 O6 P
Molecular Weight:304.24
Hs Code.:
DSSTox Substance ID:DTXSID10401781
Metabolomics Workbench ID:67107
Mol file:21064-69-7.mol

Synonyms:4-nitrophenyl-phosphorylcholine;4-nitrophenylphosphorylcholine;NPPC;para-nitrophenylphosphorylcholine

Suppliers and Price of p-Nitrophenylphosphorylcholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
NPPC
48Tests
$ 588.00

Usbiological
NPPC
48Tests
$ 588.00

TRC
4-Nitrophenylphosphorylcholine
50mg
$ 65.00

TRC
4-Nitrophenylphosphorylcholine
250mg
$ 145.00

TRC
4-Nitrophenylphosphorylcholine
1g
$ 350.00

Sigma-Aldrich
O-(4-Nitrophenylphosphoryl)choline
1g
$ 610.00

Sigma-Aldrich
O-(4-Nitrophenylphosphoryl)choline
250mg
$ 152.00

Sigma-Aldrich
O-(4-Nitrophenylphosphoryl)choline
100mg
$ 78.80

Sigma-Aldrich
O-(4-Nitrophenylphosphoryl)choline
5g
$ 2110.00

Medical Isotopes, Inc.
4-Nitrophenylphosphorylcholine
50 mg
$ 840.00

Total 10 raw suppliers

Chemical Property of p-Nitrophenylphosphorylcholine

Chemical Property:

Melting Point:216-218°C
PSA：114.22000
LogP:2.75820
Storage Temp.:−20°C
Sensitive.:Moisture & Light Sensitive
Solubility.:H2O: 0.1 g/mL, clear, faintly yellow
Water Solubility.:Soluble in water
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:304.08242326
Heavy Atom Count:20
Complexity:362

Purity/Quality:

98%,99%, ^*data from raw suppliers

NPPC ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[N+](C)(C)CCOP(=O)([O-])OC1=CC=C(C=C1)[N+](=O)[O-]
Uses 4-Nitrophenylphosphorylcholine can be used as a reagent used in Phospholipase C assay. 4-Nitrophenylphosphorylcholine (cas# 21064-69-7) is a compound useful in organic synthesis. Reported to be useful in assay of Phospholipase?C.

Technology Process of p-Nitrophenylphosphorylcholine

There total 3 articles about p-Nitrophenylphosphorylcholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-N,N,N-trimethylethan-1-aminium tetraphenylborate

: 21064-69-7
p-nitrophenyl phosphorylcholine

Guidance literature:: 4-nitro-phenol; 2-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)-N,N,N-trimethylethan-1-aminium tetraphenylborate; With 1H-tetrazole; In acetonitrile; at 25 ℃; for 0.5h; Inert atmosphere;

With tert.-butylhydroperoxide; In acetonitrile;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 25 ℃; Inert atmosphere;
DOI:10.1039/c9ob02582k

Reference yield:

: 777-52-6
1-dichlorophosphoryloxy-4-nitro-benzene

: 17773-10-3
choline iodide

: 21064-69-7
p-nitrophenyl phosphorylcholine

Guidance literature:: With quinoline; IWT<*>TMD-8 ion exchange resin; 1.) acetonitrile, 0 deg C, 5 h; 2.) acetonitrile-pyridine-water;
DOI:10.1016/0040-4039(96)01797-2