BenzenepropanaMide, 3-broMo-

Base Information

• Chemical Name: BenzenepropanaMide, 3-broMo-
• CAS No.: 615534-55-9
• Molecular Formula: C₉H₁₀BrNO
• Molecular Weight: 228.088
• Hs Code.: 2924297099
• Mol file: 615534-55-9.mol

Synonyms:3-(3-bromophenyl)propionamide

Chemical Property of BenzenepropanaMide, 3-broMo-

Chemical Property:

Purity/Quality:

98%min ^*data from raw suppliers

3-(3-Bromophenyl)propanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BenzenepropanaMide, 3-broMo-

There total 2 articles about BenzenepropanaMide, 3-broMo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-(m-bromophenyl)propionyl chloride (335159-82-5) → 3-(3-bromophenyl)propionamide (615534-55-9)

Guidance literature:

With ammonia; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield: 93.0%

3-(3-bromophenyl)propanoic acid (42287-90-1) → 3-(3-bromophenyl)propionamide (615534-55-9)

Guidance literature:

3-(3-bromophenyl)propanoic acid; With 1-hydroxy-pyrrolidine-2,5-dione; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 0.75h;

With ammonia; In dichloromethane; at 0 - 20 ℃;

Reference yield:

3-(3-bromophenyl)propionamide (615534-55-9) → 3-(3-bromophenyl)propan-1-amine (174689-12-4)

Guidance literature:

3-(3-bromophenyl)propionamide; With borane-THF; In tetrahydrofuran; at 0 - 20 ℃; for 18h;

With hydrogenchloride; water; In tetrahydrofuran; at 20 ℃; for 4h; pH=1;

With sodium hydroxide; In tetrahydrofuran; water; pH=> 10;

upstream raw materials:

3-(3-bromophenyl)propanoic acid

3-(m-bromophenyl)propionyl chloride

Downstream raw materials:

3-(3-bromophenyl)propan-1-amine

1-(3-(3-aminopropyl)phenyl)-3-ethylpent-1-yn-3-ol

tert-butyl 3-(3-bromophenyl)propylcarbamate

N-(3-(3-bromophenyl)propyl)-2,2,2-trifluoroacetamide

Refernces

• 1、 -. "ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS". Page/Page column 113-114. . Retrieved 2009/03/07.