2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione

Base Information

• Chemical Name: 2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione
• CAS No.: 213026-99-4
• Molecular Formula: C₂₅H₂₃NO₄
• Molecular Weight: 401.462
• Mol file: 213026-99-4.mol

Synonyms:2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione

Chemical Property of 2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione

There total 1 articles about 2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

phthalimide (136918-14-4,85-41-6) + dibenzyl glycerol (6972-79-8) → 2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione (213026-99-4)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1021/jm9707784

Reference yield: 86.0%

2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione (213026-99-4) → 1,3-bis(benzyloxy)propan-2-amine (132819-08-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Heating;

DOI:10.1021/jm9707784

Reference yield:

2-(2-Benzyloxy-1-benzyloxymethyl-ethyl)-isoindole-1,3-dione (213026-99-4) → 3-Benzyloxy-1-(2-benzyloxy-1-benzyloxymethyl-ethyl)-2-methyl-1H-pyridin-4-one (213026-71-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / hydrazine hydrate / ethanol / 3 h / Heating

2: aq. NaOH / ethanol / 12 h

With sodium hydroxide; hydrazine hydrate; In ethanol;

DOI:10.1021/jm9707784

upstream raw materials:

phthalimide

dibenzyl glycerol

Downstream raw materials:

1,3-bis(benzyloxy)propan-2-amine

3-Benzyloxy-1-(2-benzyloxy-1-benzyloxymethyl-ethyl)-2-methyl-1H-pyridin-4-one