6972-79-8

Basic information

• Product Name: 1,3-BIS(BENZYLOXY)-2-PROPANOL
• Synonyms: 1,3-BIS(BENZYLOXY)-2-PROPANOL;1,3-DI-O-BENZYLGLYCEROL;1,3-DIBENZYLOXY-2-PROPANOL;1,3-Dibenzylglycerol (DBG);1,3-Benzyloxy-2-propanol;1,3-Bis(phenylmethoxy)-2-propanol;1,3-Dibenzylglycerin;1,3-Dibenzyloxy-2-hydroxypropane
• CAS NO: 6972-79-8
• Molecular Formula: C₁₇H₂₀O₃
• Molecular Weight: 272.34
• Product Categories: All Aliphatics;Aliphatics;Aromatics;Intermediates
• Mol File: 6972-79-8.mol
• Article Data: 40

Chemical Properties

• Boiling Point: 226-227 °C3 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Pale-Yellow Oil
• Density: 1.103 g/mL at 20 °C(lit.)
• Vapor Pressure: 1.42E-07mmHg at 25°C
• Refractive Index: n20/D 1.549(lit.)
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 13.62±0.20(Predicted)
• BRN: 1986774
• CAS DataBase Reference: 1,3-BIS(BENZYLOXY)-2-PROPANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-BIS(BENZYLOXY)-2-PROPANOL(6972-79-8)
• EPA Substance Registry System: 1,3-BIS(BENZYLOXY)-2-PROPANOL(6972-79-8)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 6972-79-8(Hazardous Substances Data)

Usage

Chemical Properties

Pale-Yellow Oil

Uses

Different sources of media describe the Uses of 6972-79-8 differently. You can refer to the following data:
1. 1,3-Dibenzyloxy-2-propanol was used in the synthesis of 1,3-dibenzyloxyacetone. It was also used as precursor to antiviral intermediates.
2. Having spasmolytic and cholinolytic activity

InChI:InChI=1/C17H20O3/c18-17(13-19-11-15-7-3-1-4-8-15)14-20-12-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2

Upstream product

• 100-44-7 benzyl chloride 
• 56-81-5 glycerol 
• 106-89-8 epichlorohydrin 
• 100-51-6 benzyl alcohol 
• 100-39-0 benzyl bromide 
• 2930-05-4 Benzyloxymethyl-oxiran 
• 4704-76-1 4-(benzyloxymethyl)-1,3-dioxo-2-thiolane 2-oxide 
• 20194-18-7 sodium phenyl-methanolate 
• 96-23-1 1,3-Dichloro-2-propanol 
• 1708-39-0 1,2-benzylideneglycerol 
• 1708-39-0 (S)-1,2-O-benzylideneglycerol 
• 1708-40-3 2-phenyl-[1,3]dioxan-5-ol 
• 100-52-7 benzaldehyde 
• 51164-00-2 4-Benzyloxymethyl-2-phenyl-[1,3]dioxolane 

Downstream Products

• 22598-15-8 1,3-bis-benzyloxy-2-tetradecyloxy-propane 
• 97151-63-8 1,3-Dibenzyloxy-2-(4-phenylazo-benzoyloxy)-propan 
• 96002-61-8 2-Butyloxymethoxy-1,3-dibenzyloxy-propan 
• 74564-16-2 1,3-dibenzyloxy-2-(chloromethoxy)propane 
• 138208-15-8 C₂₀H₂₂O₃ 
• 138163-36-7 1,3-Di-O-benzyl-2-O-(2,3,6,2',3',4',6'-hepta-O-acetyl-β-lactosyl)glycerol 
• 138208-14-7 1,9-di-O-benzyl-2,8-bis(benzyloxymethyl)-3,7-dioxanonane 
• 157024-66-3 1,3-di-O-benzyl-2-O-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-sn-glycerol 
• 211684-58-1 (2S,3S,6S)-3-Acetoxy-6-(2-benzyloxy-1-benzyloxymethyl-ethoxy)-3,6-dihydro-2H-pyran-2-carboxylic acid methyl ester 
• 213265-19-1 (2S,3R,4S,5R,6R)-3,4,5-Tris-benzyloxy-2-(2-benzyloxy-1-benzyloxymethyl-ethoxy)-6-benzyloxymethyl-tetrahydro-pyran 
• 268567-70-0 C₂₁H₂₅ClO₃ 
• 219744-38-4 3-(2-benzyloxy-1-(benzyloxymethyl)ethoxy)-2-(2-benzyloxy-1-(benzyloxymethyl)ethoxymethyl)propene 
• 220750-68-5 succinic acid mono-(2-benzyloxy-1-benzyloxymethyl-ethyl) ester 
• 1931-78-8 2-O-hexadecylglycerol 

Relevant articles and documents

Characterization of hydrazine derivative: Proposed decomposition mechanism and structure elucidation of decomposition compounds

Decomposition of protected hydrazine diol (1) hemi-oxalate, a key intermediate of the potent indolocarbazole-based DNA topoisomerase I inhibitor (2), was investigated. Spectroscopic analysis revealed that the main decomposition compounds of the hydrazine

Selective catalytic oxidation of diglycerol

The selective oxidation of α,α-diglycerol was studied using oxygen as a clean oxidant in the presence of a palladium/neocuproine complex. After optimization of the reaction parameters, the mono-oxidation product was obtained with 93% NMR yield (up to 76% isolated yield). The product was named “diglycerose” considering that it mainly exists as a cyclic hemi-ketal form.

The role of mesoporosity and Si/Al ratio in the catalytic etherification of glycerol with benzyl alcohol using ZSM-5 zeolites

A comparative study of the influence of three different acid solids as catalysts (conventional zeolites Z15c with Si/Al = 19.5 and Z40c with Si/Al = 48.2, and a hierarchical zeolite Z40c-H with Si/Al = 50.0) for the etherification of glycerol with benzyl alcohol was performed. The catalytic activity and selectivity of these zeolites was elucidated at different catalyst contents. Three different ethers (3-benzyloxy-1,2-propanediol, which is a mono-benzyl-glycerol ether (MBG) and 1,3-dibenzyloxy-2-propanol, which is a di-benzyl-glycerol ether (DBG) and dibenzyl ether (DBz) were identified as the main products. MBG was the major product of the reaction catalyzed by the microporous Z15c zeolite with low Si/Al molar ratio, whereas DBG was formed in higher yield with the use of microporous Z40c and hierarchical Z40c-H zeolites, both of them having a similar high Si/Al molar ratio (≈50 MBG is a value-added product andit is obtained with good yield and selectivity when using the conventional zeolite Z15c as a catalyst.Under the best conditions tested, i.e., 25 mg of catalyst for 8 h at 120°C, a 62% of conversion was obtainedwithout the need of solvent, with an excellent 84% selectivity toward the MBG and no formation of DBz.