2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one

Base Information

• Chemical Name: 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one
• CAS No.: 211228-56-7
• Molecular Formula: C₃₁H₂₆O₇
• Molecular Weight: 510.543
• Mol file: 211228-56-7.mol

Synonyms:2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one

Chemical Property of 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one

There total 6 articles about 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

3',4'-bis(benzyloxy)-5,7-dihydroxy-3-methoxyflavone (1486-61-9) + methyl iodide (74-88-4) → 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one (211228-56-7) + 2-(3,4-Bis-benzyloxy-phenyl)-3,5,7-trimethoxy-chromen-4-one

Guidance literature:

With potassium carbonate; In acetone; for 2.5h; Yields of byproduct given; Heating;

Reference yield:

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone (55317-02-7) → 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one (211228-56-7)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium-<3,4-bis-benzyloxy benzoate>

2: acetone; potassium carbonate

With potassium-<3,4-bis-benzyloxy benzoate>; potassium carbonate; acetone;

Reference yield:

methyl 3,5-bis(benzyloxy)benzoate (58605-10-0) → 2-(3,4-bis-benzyloxy-phenyl)-5-hydroxy-3,7-dimethoxy-chromen-4-one (211228-56-7)

Guidance literature:

Multi-step reaction with 4 steps

1: aqueous methanol. KOH

2: SOCl₂

3: potassium-<3,4-bis-benzyloxy benzoate>

4: acetone; potassium carbonate

With potassium hydroxide; thionyl chloride; potassium-<3,4-bis-benzyloxy benzoate>; potassium carbonate; acetone;

upstream raw materials:

3',4'-bis(benzyloxy)-5,7-dihydroxy-3-methoxyflavone

dimethyl sulfate

methyl iodide

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone

Downstream raw materials:

2-(3,4-dihydroxyphenyl)-5-hydroxy-3,7-dimethoxychromen-4-one