4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol

Base Information

• Chemical Name: 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol
• CAS No.: 1029438-23-0
• Molecular Formula: C₁₂H₁₇BO₂S
• Molecular Weight: 236.143
• Mol file: 1029438-23-0.mol

Synonyms:4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol

Chemical Property of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol

Chemical Property:

• Boiling Point: 331.6±25.0 °C(Predicted)
• Density: 1.07±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol ≥97.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol

There total 1 articles about 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3-dimethyl-2,3-butane diol (76-09-5) + 4-mercaptophenylboronic acid (237429-33-3) → 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol (1029438-23-0)

Guidance literature:

With sodium sulfate; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1002/anie.202006570

Reference yield: 81.0%

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol (1029438-23-0) + allyl bromide (106-95-6) → 2-(4-(allylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (1391759-10-6)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201201409

Reference yield: 74.0%

3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one (6637-53-2,144252-21-1,144252-22-2) + 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol (1029438-23-0) → 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol)-3-phenylisoindolin-1-one

Guidance literature:

3-hydroxy-3-phenyl-2,3-dihydro-isoindol-1-one; With calcium(II) bis(trifluoromethanesulfonyl)imide; tert-butylammonium hexafluorophosphate(V); In 1,2-dichloro-ethane; at 80 ℃; for 0.0833333h;

4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenethiol; In 1,2-dichloro-ethane; at 80 ℃; for 0.25h;

DOI:10.1021/acs.joc.0c00482

upstream raw materials:

2,3-dimethyl-2,3-butane diol

4-mercaptophenylboronic acid

Downstream raw materials:

2-[4-(benzylsulfanyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

ethyl 2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thio)pent-4-enoate

2-(4-(allylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

diphenyl-{2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylsulfanyl]-ethyl}-phosphane