(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate

Base Information

• Chemical Name: (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate
• CAS No.: 125218-63-5
• Molecular Formula: C₂₅H₂₄N₂O₄
• Molecular Weight: 416.477
• Mol file: 125218-63-5.mol

Synonyms:(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate

Chemical Property of (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate

There total 1 articles about (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-nitrophenyl)propanoate (125218-62-4) → (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate (125218-63-5)

Guidance literature:

With tin(ll) chloride; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1142/S1088424621501248

Reference yield: 66.0%

succinic acid anhydride (108-30-5) + (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate (125218-63-5) → (S)-4-(4-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methoxy-3-oxopropyl)phenylamino)-4-oxobutanoic acid (1211448-01-9)

Guidance literature:

at 20 ℃;

Reference yield: 40.0%

zinc(II) 5,15-di(3,5-di-tert-butylphenyl)-10-phenylporphyrin (865535-93-9) + (S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-aminophenyl)propanoate (125218-63-5) → C79H78N6O4Zn

Guidance literature:

With sodium tetrachloroaurate(III) dihyrate; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃;

DOI:10.1142/S1088424621501248

upstream raw materials:

(S)-methyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-(4-nitrophenyl)propanoate

Downstream raw materials:

methyl (S)-2-amino-3-[4-(benzyloxycarbonylamino)phenyl]propionate

(S)-3-(4-Amino-phenyl)-2-[5-((3aR,6S,6aS)-2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoylamino]-propionic acid

(S)-4-(4-(2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-methoxy-3-oxopropyl)phenylamino)-4-oxobutanoic acid