(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Base Information

Chemical Name:(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester
CAS No.:181767-64-6
Molecular Formula:C₂₀H₂₃N₅O₅
Molecular Weight:413.433
Hs Code.:

Synonyms:(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Suppliers and Price of (S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

There total 3 articles about (S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-azidomethyl-2-(4-tert-butoxy-phenyl)-ethylamine

: 7693-46-1
4-Nitrophenyl chloroformate

: 181767-64-6
(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1021/acscombsci.6b00160

Reference yield:

: [(S)-2-(4-tert-Butoxy-phenyl)-1-hydroxymethyl-ethyl]-carbamic acid 2-trimethylsilanyl-ethyl ester

: 181767-64-6
(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) MsCl, 2.) NaN₃ / 1.) TEA, THF, 0 deg C, 2.) DMF, 55 - 60 deg CI

2: 1.) TBAF, 2.) pyridine / 1.) CH₃CN, 2.) THF

With pyridine; sodium azide; tetrabutyl ammonium fluoride; methanesulfonyl chloride;
DOI:10.1016/0040-4039(96)01100-8

Reference yield:

: 7693-46-1
4-Nitrophenyl chloroformate

: [(S)-1-Azidomethyl-2-(4-tert-butoxy-phenyl)-ethyl]-carbamic acid 2-trimethylsilanyl-ethyl ester

: 181767-64-6
(S)-[2-azido-1-(4-tert-butoxy-benzyl)ethyl]carbamic acid 4-nitrophenyl ester

Guidance literature:: With pyridine; tetrabutyl ammonium fluoride; Yield given. Multistep reaction; 1.) CH₃CN, 2.) THF;
DOI:10.1016/0040-4039(96)01100-8