Technology Process of (Z)-But-2-enedioic acid ethyl ester 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester
There total 6 articles about (Z)-But-2-enedioic acid ethyl ester 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
dmap; dicyclohexyl-carbodiimide;
In
dichloromethane;
for 4h;
Ambient temperature;
DOI:10.1039/c39840001423
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1) LDA / 1) THF, -78 degC
2: 78 percent / NaH / tetrahydrofuran / 4 h / Heating
3: 79 percent / p-TsOH / benzene / 24 h / Heating
4: 96 percent / diethyl ether / 4 h / Heating
5: 70 percent / LiAlH4 / diethyl ether / 2 h / Heating
6: 67 percent / dicyclohexylcarbodiimide, 4(N,N-dimethylamino)pyridine / CH2Cl2 / 4 h / Ambient temperature
With
dmap; lithium aluminium tetrahydride; sodium hydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; dichloromethane; benzene;
DOI:10.1039/c39840001423
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 78 percent / NaH / tetrahydrofuran / 4 h / Heating
2: 79 percent / p-TsOH / benzene / 24 h / Heating
3: 96 percent / diethyl ether / 4 h / Heating
4: 70 percent / LiAlH4 / diethyl ether / 2 h / Heating
5: 67 percent / dicyclohexylcarbodiimide, 4(N,N-dimethylamino)pyridine / CH2Cl2 / 4 h / Ambient temperature
With
dmap; lithium aluminium tetrahydride; sodium hydride; toluene-4-sulfonic acid; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; diethyl ether; dichloromethane; benzene;
DOI:10.1039/c39840001423
