114298-66-7

Upstream product

• 60078-92-4 2,4,4-trimethyl-3-formyl-2-cyclohexen-1-ol 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 1629-58-9 4-penten-3-one 
• 64095-45-0 2,2-dimethyl-5-oxo-heptanoic acid methyl ester 
• 63184-86-1 2,6,6-trimethylcyclohexane-1,3-dione 
• 14398-36-8 (3E)-4-[(S)-2,6,6-trimethylcyclohex-2-enyl]but-3-en-2-one 
• 37677-81-9 (rac)-4-(2,3-epoxy-2,6,6-trimethylcyclohexyl)-3-buten-2-one 
• 174910-90-8 3-methoxy-2,6,6-trimethylcyclohex-2-en-1-one 
• 127-41-3 alpha-ionone 
• 190059-33-7 (E)-4-(1,3,3-Trimethyl-7-oxa-bicyclo[4.1.0]hept-2-yl)-but-3-en-2-one 
• 60078-91-3 2,3-epoxy-2,6,6-trimethylcyclohexane-1-carboxaldehyde 
• 19493-09-5 Methylenetriphenylphosphorane 
• 85679-49-8 2,4,4-trimethyl-3-vinyl-cyclohex-2-enone 
• 1031-15-8 methyltriphenylphosphonium chloride 

Downstream Products

• 104788-47-8 (Z)-But-2-enedioic acid ethyl ester 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester 
• 104788-50-3 (E)-But-2-enedioic acid ethyl ester 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester 
• 121463-10-3 But-2-ynoic acid 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester 
• 104788-48-9 (Z)-But-2-enedioic acid methyl ester 2,4,4-trimethyl-3-vinyl-cyclohex-2-enyl ester 
• 114250-63-4 (8aR,8bR)-6,6,8b-Trimethyl-3-(toluene-4-sulfonyl)-4,6,7,8,8a,8b-hexahydro-naphtho[1,8-bc]furan-2-one 
• 116428-59-2 6-But-2-ynyloxy-1,3,3-trimethyl-2-vinyl-cyclohexene 
• 125417-01-8 1,3,3-Trimethyl-6-prop-2-ynyloxy-2-vinyl-cyclohexene 
• 97760-29-7 (S)-(-)-2,4,4-trimethyl-3-vinyl-2-cyclohexen-1-ol 
• 85679-49-8 2,4,4-trimethyl-3-vinyl-cyclohex-2-enone 
• 854764-44-6 (R)-tert-butyl-dimethyl-(2,4,4-trimethyl-3-vinyl-cyclohex-2-enyloxy)-silane 
• 123286-37-3 (R)-2,4,4-trimethyl-3-vinyl-2-cyclohexene-1-ol 

Relevant academic research and scientific papers

AN APPROACH TO FORSKOLIN AN EFFICIENT SYNTHESIS OF A TRICYCLIC LACTONE INTERMEDIATE

Tricyclic lactone l0, a potential intermediate for the synthesis of forskolin, was prepared from (+/-)-3-hydroxycyclocitral employing an intramolecular Michael addition as the key step.

Microbial synthesis of optically pure (R)-2,4,4-trimethyl-3-(2'-hydroxyethyl)-cyclohex-2-en-1-ol, a new and versatile chiral building block for terpene synthesis

The hydroxylation of 2,4,4-trimethyl-3-(2'-hydroxyethyl)-2-cyclohexene by Mucor plumbeus, after usual work up and a subsequent single crystallization, gave the corresponding optically pure (1R)-hydroxy synthon.

Enantioselective synthesis of 1(R)-hydroxypolygodial

Enantioselective preparation of 1(R)-hydroxypolygodial (5) has been achieved starting from α-ionone through a synthetic strategy involving a Corey-Bakshi-Shibata oxazaborolidine-mediated reduction and a stereoselective Diels-Alder reaction as key steps.

Total synthesis of forskolin - Part I

A new total synthesis of forskolin 1 has been achieved and this note describes the synthesis of the transfused enone 18 as a key-intermediate. Key steps are: 1) the intramolecular Diels-Alder reaction of 17 to afford the tricyclic lactone 8 (48-56%); 2) a

An Efficient Approach to the AB Ring System of Forskolin

An efficient intramolecular Diels-Alder reaction for the synthesis of the AB ring system of forskolin is described.

An Intramolecular Diels-Alder Strategy to Forskolin

A strategy for the construction of the AB ring system of forskolin based on a novel intramolecular Diels-Alder reaction is reported.