2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Base Information

Chemical Name:2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole
CAS No.:178981-88-9
Molecular Formula:C₂₆H₂₅Cl₂N₃OS
Molecular Weight:498.476
Hs Code.:

Synonyms:2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

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Technology Process of 2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

There total 2 articles about 2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 2-benzyloxymethyl-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole dinitrate

: 74282-78-3
3,5-dichlorobenzenesulfenyl chloride

: 178981-88-9
2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Guidance literature:: 2-benzyloxymethyl-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole dinitrate; With sodium hydroxide; In water; toluene;

3,5-dichlorobenzenesulfenyl chloride; With triethylamine; In toluene; at 0 ℃; for 3.5h; Product distribution / selectivity;

Reference yield:

: 209743-77-1
2-benzyloxymethyl-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

: 74282-78-3
3,5-dichlorobenzenesulfenyl chloride

: 178981-88-9
2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Guidance literature:: With 4-methyl-morpholine; In toluene; at 0 - 20 ℃; Product distribution / selectivity;

Reference yield: 82.0%

: 178981-88-9
2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

: 178981-89-0
2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Guidance literature:: 2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole; With hydrogenchloride; water; at 90 ℃; for 2h;

With sodium hydroxide; In water; Product distribution / selectivity;