{5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol

Base Information

Chemical Name:{5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol
CAS No.:178981-89-0
Molecular Formula:C19H19 Cl2 N3 O S
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID90431723
Nikkaji Number:J1.647.948I
Wikidata:Q82245683
ChEMBL ID:CHEMBL576564
Mol file:178981-89-0.mol

Synonyms:178981-89-0;{5-[(3,5-DICHLOROPHENYL)SULFANYL]-4-ISOPROPYL-1-((PYRIDIN-4-YL)METHYL)IMIDAZOL-2-YL}METHANOL;[5-(3,5-dichlorophenyl)sulfanyl-4-propan-2-yl-1-(pyridin-4-ylmethyl)imidazol-2-yl]methanol;{5-[(3,5-DICHLOROPHENYL)SULFANYL]-4-ISOPROPYL-1-(PYRIDIN-4-YLMETHYL)IMIDAZOL-2-YL}METHANOL;CHEMBL576564;SCHEMBL5852651;DTXSID90431723;[5-(3,5-dichlorophenyl)sulfanyl-4-isopropyl-1-(4-pyridylmethyl)imidazol-2-yl]methanol;[5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(4-pyridylmethyl)-1H-imidazole-2-yl]methanol;2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole;5-(3,5-Dichlorophenylthio)-4-isoproyl-1-(4-pyridylmethyl)-2-hydroxymethyl-1H-imidazole;{5-[(3,5-Dichlorophenyl)sulfanyl]-4-(propan-2-yl)-1-[(pyridin-4-yl)methyl]-1H-imidazol-2-yl}methanol

Suppliers and Price of {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol

Chemical Property:

PSA：76.24000
LogP:5.40010
XLogP3:4.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:407.0625888
Heavy Atom Count:26
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=C(N(C(=N1)CO)CC2=CC=NC=C2)SC3=CC(=CC(=C3)Cl)Cl

Technology Process of {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol

There total 2 articles about {5-[(3,5-Dichlorophenyl)sulfanyl]-4-isopropyl-1-((pyridin-4-YL)methyl)imidazol-2-YL}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.9%

: 2-acetyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

: 178981-89-0
2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Guidance literature:: With sodium hydroxide; ethanol; water; at 0 ℃; for 0.5h; Product distribution / selectivity;

Reference yield: 82.0%

: 178981-88-9
2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

: 178981-89-0
2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

Guidance literature:: 2-Benzyloxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole; With hydrogenchloride; water; at 90 ℃; for 2h;

With sodium hydroxide; In water; Product distribution / selectivity;

Reference yield: 93.2%

: 1189-71-5
isocyanate de chlorosulfonyle

: 178981-89-0
2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole

: 178979-85-6
capravirine

Guidance literature:: isocyanate de chlorosulfonyle; 2-Hydroxymethyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-(pyridin-4-yl)methyl-1H-imidazole; In ethyl acetate; at -30 - 20 ℃; for 1.5h;

With hydrogenchloride; water; In ethyl acetate; at -30 - 40 ℃; for 1h;

With sodium carbonate; In water; ethyl acetate; at 20 ℃; Product distribution / selectivity;