4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI)

Base Information

• Chemical Name: 4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI)
• CAS No.: 205874-34-6
• Molecular Formula: C₁₀H₁₇N
• Molecular Weight: 151.252
• Mol file: 205874-34-6.mol

Synonyms:4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI)

Chemical Property of 4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI)

There total 16 articles about 4,7-Methano-1H-inden-5-amine,octahydro-,(4R,5R,7R)-rel-[partial]-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Tricyclo[5.2.1.02,6]decan-8-onoxim (6319-15-9) → 8-endo-Aminotricyclo[5.2.1.02,6]decan (669-51-2,18530-46-6,18530-47-7,73335-94-1,205874-34-6)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether; for 24h; Heating;

Reference yield:

(+/-)-(3ac,7ac)-octahydro-4r,7c-methano-inden-5-one oxime (6319-15-9,73365-80-7) → (+/-)-(3ac,7ac)-octahydro-4r,7c-methano-inden-5t-ylamine (669-51-2,18530-46-6,18530-47-7,73335-94-1,205874-34-6)

Guidance literature:

With ethanol; sodium;

DOI:10.1021/ja01512a037

Reference yield:

(+/-)-(3ac,7ac)-1,3a,4,6,7,7a-hexahydro-4r,7c-methano-inden-5-one oxime (7142-70-3,123288-65-3) → (+/-)-(3ac,7ac)-octahydro-4r,7c-methano-inden-5t-ylamine (669-51-2,18530-46-6,18530-47-7,73335-94-1,205874-34-6)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

2: sodium; ethanol

With ethanol; sodium; platinum;

DOI:10.1021/ja01512a037

upstream raw materials:

(+/-)-(3ac,7ac)-octahydro-4r,7c-methano-inden-5-one oxime

(+/-)-(3ac,7ac)-1,3a,4,6,7,7a-hexahydro-4r,7c-methano-inden-5-one oxime

Tricyclo[5.2.1.0^2,6]decan-8-onoxim

(+/-)-(3ac,7ac)-3a,4,5,6,7,7a-hexahydro-4r,7c-methano-inden-5c-ylamine

Downstream raw materials:

C₂₇H₃₂ClN₃O₅S

C₂₇H₃₃N₃O₅S

C₂₈H₃₅N₃O₅S

C₂₆H₃₁N₃O₄S