6319-15-9

Usage

Uses

Used in Organic Synthesis:
(5E)-N-hydroxyoctahydro-5H-4,7-methanoinden-5-imine is used as a versatile intermediate for the synthesis of a range of organic compounds. Its unique chemical reactivity allows it to participate in various chemical reactions, making it a valuable building block in the production of fine chemicals.
Used in Pharmaceutical Research:
(5E)-N-hydroxyoctahydro-5H-4,7-methanoinden-5-imine is used as a key intermediate in the development of pharmaceuticals. Its structural and functional properties make it an important target for research and development in the field of medicinal chemistry and drug discovery. It can be utilized in the synthesis of new drug candidates and the improvement of existing pharmaceuticals.
Used in Agrochemicals:
(5E)-N-hydroxyoctahydro-5H-4,7-methanoinden-5-imine is also used in the agrochemical industry as a building block for the synthesis of various agrochemicals. Its unique properties and reactivity make it a valuable component in the development of new and improved agrochemical products.

Upstream product

• 34748-64-6 exo-2,exo-6-tricyclo[5.2.1.0^2.6]decan-8-one 
• 10271-42-8 Octahydro-endo-4,7-methanoinden-endo-5-ol 
• 2826-19-9 (3aR^*,4S^*,7R^*,7aS^*)-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene 
• 142-29-0 cyclopentene 
• 542-92-7 cyclopenta-1,3-diene 
• 7142-70-3 (+/-)-(3ac,7ac)-1,3a,4,6,7,7a-hexahydro-4r,7c-methano-inden-5-one oxime 

Downstream Products

• 669-51-2 8-exo-Aminotricyclo<5.2.1.0^2,6>decan 
• 669-51-2 8-endo-Aminotricyclo[5.2.1.0^2,6]decan 
• 669-51-2 (+/-)-(3ac,7ac)-octahydro-4r,7c-methano-inden-5t-ylamine 
• 205874-34-6 Exo-5.6-trimethylen-nor-bornan-2-endo-amin 
• 205874-34-6 8-Amino-tricyclo<5.2.1.0^2,6>decan 

Relevant academic research and scientific papers

Synthesis of certain unsubstituted, 9-exo-(dialkylaminomethyl)-, and 9- endo-(aralkyl)-tricyclo [5.2.1.02,6 decane-8-ketoxime esters and ethers with local anesthetic and analgesic activities

The synthesis of series of unsubstituted, 9-exo-(dialkylaminomethyl)-, and 9-endo-(aralkyl)tricyclo [5.2.1.0(2,6)] decane-8-ketoximes esters and ethers 3a-j, 4a-d, 7a-j and 13a-d from the oxime synthons 2, 6a-e, 12a and 12b, respectively, is described. Al

BECKMANN REACTION OF FRAMEWORK SUBSTRATES. III. REACTION OF KETONES OF THE TRICYCLO2,6>DECANE SERIES WITH HYDROXYLAMINE-O-SULFONIC ACID IN ORGANIC AND AQUEOUS ORGANIC SOLVENTS

The possibility of the preparative realization of the Beckmann reaction with hydroxylamine-O-sulfonic acid in a homogeneous medium was demonstrated for the case of tricyclo2,6>dec-3-en-9-one and tricyclo2,6>dec-4-en-9-one.The intermediate reaction products (oxime sulfates) were isolated in the form of the ammonium salts.They are converted into the same lactams and bicyclic unsaturated hydroxynitriles as the ketones in the direct reaction.In acetonitrile the corresponding acetaminonitriles are formed instead of the hydroxynitriles.In anhydrousorganic solvents or with a small content of water the direction of the process changes toward the preferential formation of the oximes.The nature of the dependence of the solvolysis rate on the acceptor and donor numbers of tetrahydrofuran, dioxane, acetone, dimethylformamide, and dimethyl sulfoxide confirms the carbenium-ion mechanism of the process.