Technology Process of C15H15N3O2
There total 3 articles about C15H15N3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-[6-(cyclopropylmethyl-amino)-pyrimidin-4-yl]-benzoic acid methyl ester;
With
sodium hydroxide;
In
methanol; water;
at 40 ℃;
for 18h;
With
hydrogenchloride;
In
methanol; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium carbonate / bis-triphenylphosphine-palladium(II) chloride / 1,2-dimethoxyethane; ethanol; water / 15 h / 130 °C / CEM microwave
2: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 0.5 h / 120 °C / Microwave
3: sodium hydroxide / methanol; water / 18 h / 40 °C
With
sodium hydroxide; sodium carbonate; N-ethyl-N,N-diisopropylamine;
bis-triphenylphosphine-palladium(II) chloride;
In
methanol; 1,2-dimethoxyethane; ethanol; water; isopropyl alcohol;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 0.5 h / 120 °C / Microwave
2: sodium hydroxide / methanol; water / 18 h / 40 °C
With
sodium hydroxide; N-ethyl-N,N-diisopropylamine;
In
methanol; water; isopropyl alcohol;