2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester

Base Information

Chemical Name:2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester
CAS No.:115787-62-7
Molecular Formula:C₁₆H₁₅N₅O₅
Molecular Weight:357.326
Hs Code.:

Synonyms:2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester

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Technology Process of 2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester

There total 1 articles about 2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6731-58-4
ethyl 2-cyano-3-phenylpropanoate

: 1007-99-4
2-amino-6-chloro-5-nitro-3H-pyrimidine-4-one

: 115787-62-7
2-amino-α-cyano-1,6-dihydro-5-nitro-6-oxo-α-(phenylmethyl)-4-pyrimidineacetic acid ethyl ester

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, RT, 15 min, 2.) DMF, 65 deg C, 24 h;
DOI:10.1021/jm00087a015