(1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

Base Information

Chemical Name:(1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate
CAS No.:1033881-27-4
Molecular Formula:C₂₇H₄₁N₅O₅
Molecular Weight:515.653
Hs Code.:

Synonyms:(1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

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Chemical Property of (1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

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Technology Process of (1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

There total 1 articles about (1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 402958-96-7
(S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid

: 837359-97-4,161618-52-6
(1R,2S)-2-amino-cyclohexanecarboxylic acid methyl ester

: 1033881-27-4
(1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

Guidance literature:: (S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 25 ℃; for 0.333333h;

(1R,2S)-2-amino-cyclohexanecarboxylic acid methyl ester; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 1033881-27-4
(1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate

: 1033881-29-6
(1R,2S)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylic acid

Guidance literature:: (1R,2S)-methyl 2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanamido)cyclohexanecarboxylate; With sodium hydroxide; In ethanol; at 20 ℃; for 2h;

With hydrogenchloride; In ethanol;