1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene

Base Information

• Chemical Name: 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene
• CAS No.: 263157-59-1
• Molecular Formula: C₁₇H₂₆O₂
• Molecular Weight: 262.392
• Mol file: 263157-59-1.mol

Synonyms:1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene

Chemical Property of 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene

There total 4 articles about 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

prenyl bromide (870-63-3) + 1-isopropyl-2-methoxymethoxy-3-methyl-benzene (263157-58-0) → 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene (263157-59-1)

Guidance literature:

1-isopropyl-2-methoxymethoxy-3-methyl-benzene; With sec.-butyllithium; In tetrahydrofuran; at -78 - 30 ℃; for 2h;

prenyl bromide; at -78 ℃; for 1h; Further stages.;

DOI:10.1021/jo9919613

Reference yield:

2-(1-methylethyl)phenol (88-69-7) → 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene (263157-59-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / NaH / tetrahydrofuran / 2.5 h / 6.5 °C

2: 98 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

3: 98 percent / s-BuLi / tetrahydrofuran / 2 h / 20 °C

With n-butyllithium; sec.-butyllithium; sodium hydride; In tetrahydrofuran; 1: Methylation / 2: Methylation / 3: Addition;

DOI:10.1021/ja993598n

Reference yield:

1-isopropyl-2-methoxymethyloxybenzene (74931-59-2) → 1-Isopropyl-2-methoxymethoxy-3-(4-methyl-pent-3-enyl)-benzene (263157-59-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / n-BuLi / tetrahydrofuran / -78 - 20 °C

2: 98 percent / s-BuLi / tetrahydrofuran / 2 h / 20 °C

With n-butyllithium; sec.-butyllithium; In tetrahydrofuran; 1: Methylation / 2: Addition;

DOI:10.1021/ja993598n

upstream raw materials:

1-isopropyl-2-methoxymethyloxybenzene

prenyl bromide

methyl iodide

1-isopropyl-2-methoxymethoxy-3-methyl-benzene

Downstream raw materials:

1-Isopropyl-2-methoxy-3-(4-methyl-pent-3-enyl)-benzene

2-isopropyl-6-(4-methyl-pent-3-enyl)-phenol

(E)-5-(3-Isopropyl-2-methoxymethoxy-phenyl)-2-methyl-pent-2-en-1-ol

1-((E)-5-Bromo-4-methyl-pent-3-enyl)-3-isopropyl-2-methoxymethoxy-benzene